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Automated Autoradiographic Analysis of Tumor Cell Colonies in vitro

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Biological Dosimetry

Abstract

The studies reported below are basic to the design of therapeutic strategies against cancer and to the understanding of therapeutic effects. It is unlikely that clinical therapy could employ the same methodology, however, so this approach could not be incorporated into “kinetics-directed” therapy. As defined and implemented successfully by Barranco et al. (1982a, b), therapy is kinetics-directed when the kinetic properties of cell populations under treatment are actually determined and used to schedule the timing of multiple treatments. Thus, the substance of this paper is of potential importance to kinetics-based cancer therapy, i.e. using historical or empirical data to formulate models.

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© 1984 Springer-Verlag Berlin Heidelberg

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Kallman, R.F. (1984). Automated Autoradiographic Analysis of Tumor Cell Colonies in vitro. In: Eisert, W.G., Mendelsohn, M.L. (eds) Biological Dosimetry. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-69334-2_23

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  • DOI: https://doi.org/10.1007/978-3-642-69334-2_23

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-12790-1

  • Online ISBN: 978-3-642-69334-2

  • eBook Packages: Springer Book Archive

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