Results of Animal Experiments With Balloon Dilatation

  • C. L. Zollikofer
  • W. R. Castaneda-Zuniga
  • K. Amplatz


We have recently described a new concept, based on animal and human cadaver studies, which suggests that intimai disruption and medial stretching rather than remodeling or compression of atherosclerotic plaques represent the probable mechanism for increase in the diameter of the lumen after percutaneous transluminal angioplasty (PTA) [1, 2]. Similar findings have been reported by other authors, although some of them do not exclude plaque compression and mention the possibility of desquamation of superficial plaque elements [3–6].


Atherosclerotic Plaque Balloon Inflation Internal Elastic Lamina Rabbit Aorta Balloon Size 
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  1. 1.
    Castaneda-Zuniga WR, Formanek A, Tadavarthy M et al. (1980) The mechanism of balloon angioplasty. Radiology 135: 565–571.PubMedGoogle Scholar
  2. 2.
    Castaneda-Zuniga WR, Amplatz K, Laerum F et al. (1981) Mechanics of angioplasty: an experimental approach. Radiographics 1: 1–14.Google Scholar
  3. 3.
    Block PC, Baughman KL, Pasternak RC et al. (1980) Transluminal angioplasty: correlation of morphologic and angiographic findings in an experimental model. Circulation 61: 778–785.PubMedGoogle Scholar
  4. 4.
    Block PC, Fallon JT, Elmer D (1980) Experimental angioplasty: lessons from the laboratory. AJR 135: 907–912.PubMedGoogle Scholar
  5. 5.
    Hoffmann MA, Fallon JT, Greenfield AJ et al. (1981) Arterial pathology after percutaneous transluminal angioplasty. AJR 137: 147–149.Google Scholar
  6. 6.
    Saffitz JE, Totty WG, McClennan BL et al. (1981) Percutaneous transluminal angioplasty. Radiology 141: 651–654.PubMedGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1983

Authors and Affiliations

  • C. L. Zollikofer
  • W. R. Castaneda-Zuniga
  • K. Amplatz

There are no affiliations available

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