The Morphological Concept of Percutaneous Transluminal Angioplasty
Since the introduction of percutaneous transluminal angioplasty (PTA), the question of the destiny of the obliterating arteriosclerotic material after the perforating or dilating procedure has been widely discussed. Several possibilities have been mentioned, such as compression of the intimai cushions, lysis of intimai appositions, dilatation of the vessel wall including the media, radial rupture of the intima, and loosening of intimai plaques with embolization into the periphery [1–8]. In reality the spectrum of morphological alterations is as complex as the morphological pattern of arteriosclerosis itself. Any of the mentioned possibilities may occur. Only by evaluating the type of arteriosclerotic lesion can we understand the chances of PTA and the possible reasons for failure and for certain complications. In spite of the latter, PTA has gained a definite position within the therapy spectrum of obliterating arterial disease.
KeywordsIntimal Proliferation Dense Connective Tissue Cholesterin Granuloma Thrombotic Material Spontaneous Dissection
Unable to display preview. Download preview PDF.
- 1.Baughman KL, Pasternak RC, Fallon JT, Block PC (1978) Coronary transluminal angioplasty in autopsied human hearts. Circulation 58(2): 11–80.Google Scholar
- 3.Castanega-Zunida WR, Formanek A, Tadavarthy M (1980) The mechanism of balloon angioplasty. Radiology 135:565.Google Scholar
- 4.Freudenberg H, Wefing H, Lichtlen PR (1978) Risks of transluminal coronary angioplasty: a postmortem study. Circulation 58(2): 11–80.Google Scholar
- 6.Leu HJ, Grüntzig A (1978) Histopathologic aspects of transluminal recanalization. In: Zeitler E, Grüntzig A, Schoop W (eds) Percutaneous vascular recanalization. Springer, Berlin Heidelberg New York, pp 39–50.Google Scholar
- 8.Simpson JB, Robert EW, Tillingham ME, Myler R, Harrison DC (1978) Coronary transluminal angioplasty in human cadaver hearts. Circulation 58(2): 11–80.Google Scholar