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Pharmacology of the Eye pp 193–248Cite as

Autonomic Nervous System: Adrenergic Agonists

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Part of the book series: Handbook of Experimental Pharmacology ((HEP,volume 69))

Abstract

Increased understanding of the adrenergic nervous system has occurred because of the availability of radiolabeled catecholamines of high specific activity and the development of biochemical and histofluorescent methods for measuring catecholamines and the biological responses to them with a high degree of sensitivity. Interest in applying the tools of contemporary adrenergic pharmacology to the eye stems from several sources:

  1. 1.

    The uveal tract, especially the iris, is a place of very rich noradrenergic innervation, and the eye and its fluid chambers are suited for investigation of basic mechanisms.

  2. 2.

    The adrenergic nervous system participates in several ocular regulatory and neurotransmitter mechanisms.

  3. 3.

    A possible role for adrenergic dysregulation exists in certain disease states.

  4. 4.

    Adrenergic compounds are relied upon in the treatment of glaucoma.

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  1. Department of Ophthalmology and Visual Science, School of Medicine, Yale University, 333 Cedar Street, New Haven, CT, 06510, USA

    Marvin L. Sears

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Sears, M.L. (1984). Autonomic Nervous System: Adrenergic Agonists. In: Sears, M.L. (eds) Pharmacology of the Eye. Handbook of Experimental Pharmacology, vol 69. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-69222-2_5

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