Pressure Volume Changes in Isobaric Brain Impaction

  • A. Marmarou
  • T. Nakamura
  • K. Tanaka
  • K. Shapiro
Conference paper

Abstract

The relationship of intracranial pressure and brain edema is not clear. Increased intracranial pressure, as would be expected, has not been a consistent finding in studies attempting to define the changes of intracranial pressure (ICP) associated with laboratory models of brain edema. In our experience, both cryogenic and infusion models of edema have produced relatively mild increases of ICP despite significant increases in brain tissue water (1, 2). We hypothesised that the rate of edema was an important factor and in this study challenged the brain with a high rate of infused volume at multiple locations in order to define more clearly the pressure dynamics.

Keywords

Intracranial Pressure Brain Edema Edema Formation Infusion Model Tissue Pressure 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Marmarou, A., Shulman, K., Shapiro, K., and Poll, W: The time course of tissue pressure and local CBF in vasogenic edema. In: Dynamics of Brain Edema, H.M. Pappius, W. Feindel (eds.) Springer-Verlag, Berlin, Heidelberg, New York, pp 113–121, 1976CrossRefGoogle Scholar
  2. Walstra, G., Takagi, H., Marmarou, A., Shulman, K., Shapiro, K: The time course of brain tissue compliance and resistance in a controlled model of brain edema. In: Intracranial Pressure IV, Shulman, K., Marmarou, A., Miller, JD, Becker, DP, Hochwald, GM, and Brock, M. (eds), Berlin, Heidelberg, New York, Springer-Verlag, pp. 253–256, 1980CrossRefGoogle Scholar
  3. Marmarou, A., Shulman, K., and Rosende, R: A nonlinear analysis of the cerebrospinal fluid system and intracranial pressure dynamics. J. Neurosurg. 48:332–344, 1978PubMedCrossRefGoogle Scholar
  4. Marmarou, A., Shulman, K., and LaMorgese, J: A comPartmental analysis of compliance and outflow resistance of the CSF system. J. Neurosurg. 43:523–534, 1975PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin · Heidelberg 1983

Authors and Affiliations

  • A. Marmarou
    • 1
  • T. Nakamura
    • 1
  • K. Tanaka
    • 1
  • K. Shapiro
    • 1
  1. 1.Division of NeurosurgeryMCV Station-Medical College of VirginiaRichmondUSA

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