Advertisement

Konservative Therapie der chronischen Pankreatitis

Conference paper
Part of the Interdisziplinäre Gastroenterologie book series (GASTROENTEROLOG)

Zusammenfassung

Eine kausale medikamentöse oder diätetische Therapie der chronischen Pankreatitis gibt es nicht; die konservative Behandlung beschränkt sich auf symptomatische Maßnahmen und konzentriert sich auf 3 Ziele:
  1. 1)

    den Versuch, weitere Pankreatitisschübe zu verhindern,

     
  2. 2)

    die Schmerzbehandlung, falls notwendig,

     
  3. 3)

    die Substitution einer allfälligen endokrinen und exokrinen Pan-kreasinsuffizienz.

     

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

  1. 1.
    Ammann R (1970) Die chronische Pankreatitis. Dtsch Med Wochenschr 95:1–7PubMedCrossRefGoogle Scholar
  2. 2.
    Ammann R (1979) Langzeitverlauf und Therapie der chronisch-rezidivierenden Pankreatitis. Internist (Berlin) 20:392–398Google Scholar
  3. 3.
    DiMagno EP (1979) Medical treatment of pancreatic insufficiency. Mayo Clin Proc 54:435–442PubMedGoogle Scholar
  4. 4.
    DiMagno EP, Go VLW, Summerskill WHJ (1973) Relations between pancreatic enzyme outputs and malabsorption in severe pancreatic insufficiency. N Engl J Med 288:813–815PubMedCrossRefGoogle Scholar
  5. 5.
    DiMagno EP, Malagelada JR, Go VLW, Moertel CG (1977) Fate of orally ingested enzymes in pancreatic insufficiency. N Engl J Med 296:1318–1322PubMedCrossRefGoogle Scholar
  6. 6.
    Durie PR, Bell L, Linton W, Corey ML, Forstner GG (1980) Effect of Cimetidine and sodium bicarbonate on pancreatic replacement therapy in cystic fibrosis. Gut 21:778–786PubMedCrossRefGoogle Scholar
  7. 7.
    Economou G, Ward-McQuaid JH (1971) A cross-over comparison of the effect of morphine, pethidine, pentazocine and phenazocine on biliary pressure. Gut 12:218–221PubMedCrossRefGoogle Scholar
  8. 8.
    Gow R, Francis P, Bradbear R, Shepherd R (1981) Comparative study of varying regimens to improve steatorrhoea and creatorrhoea in cystic fibrosis: effectiveness of enteric-coated preparations with and without antacids and Cimetidine. Lancet 11:1071–174CrossRefGoogle Scholar
  9. 9.
    Graham DY (1977) Enzyme replacement therapy of exocrine pancreatic insufficiency inman. N Engl J Med 296:1314–1317PubMedCrossRefGoogle Scholar
  10. 10.
    Ihse I, Isaksson G (1982) Pain-relieving effect of pancreatic enzyme preparations in chronic pancreatitis (Abstract). Scand J Gastroenterol [Suppl 17] 78:401Google Scholar
  11. 11.
    Ihse J, Lilja P (1979) Pancreatic enzyme activities of commercial pancreatic enzyme preparations incubated in human small intestinal juice. Digestion 19:48–51PubMedCrossRefGoogle Scholar
  12. 12.
    Joffe BI, Bank S, Marks IN (1968) Hypoglycaemia in pancreatitis. Lancet II:1038CrossRefGoogle Scholar
  13. 13.
    Linde J, Nilsson LH, Barany FR (1977) Diabetes and hypoglycemia in chronic pancreatitis. Scand J Gastroenterol 12:369–373PubMedCrossRefGoogle Scholar
  14. 14.
    MacLaren IF, Howard JM, Serlin O (1966) Achlorhydria associated with chronic disease of the exocrine pancreas. Surgery 59:676–680PubMedGoogle Scholar
  15. 15.
    Möller H (1979) Vergleichende Untersuchungen von Pankreatin-Fertigarzneimitteln. Pharmazeut Z 124:2279–2286Google Scholar
  16. 16.
    Regan PT, Malagelada JR, DiMagno EP, Glanzman SL, Go VLW (1977) Comparative effects of antacids, Cimetidine and enteric coating on therapeutic response to oral enzymes in severe pancreatic insufficiency. N Engl J Med 297:854–858PubMedCrossRefGoogle Scholar
  17. 17.
    Regan PT, Malagelada JR, DiMagno EP, Go VLW (1978) Rationale for the use of Cimetidine in pancreatic insufficiency. Mayo Clin Proc 53:79–83PubMedGoogle Scholar
  18. 18.
    Regan PT, Malagelada JR, DiMagno EP, Go VLW (1979) Reduced intraluminal bile acid concentrations and fat maldigestion in pancreatic insufficiency: correction by treatment. Gastroenterology 77:285–289PubMedGoogle Scholar
  19. 19.
    Sarles H, Sahel J, Staub JL, Bourry J, Laugier R (1979) Chronic pancreatitis. In: Howat HR, Sarles H (eds) The exocrine pancreas. Saunders, London Philadelphia TorontoGoogle Scholar
  20. 20.
    Sarles JC, Sarles H (1976) Konservative und chirurgische Therapie der chronischen Pankreatitis. Leber Magen Darm 6:294–299PubMedGoogle Scholar
  21. 21.
    Saunders JHB, Wormsley KG (1975) Progress report. Pancreatic extracts in the treatment of pancreatic exocrine insufficiency. Gut 16:157–162PubMedCrossRefGoogle Scholar
  22. 22.
    Saunders JHB, Drummond S, Wormsley KG (1977) Inhibition of gastric secretion in treatment of pancreatic insufficiency. Br Med J 1:418–419PubMedCrossRefGoogle Scholar
  23. 23.
    Saunders JHB, Cargill JM, Wormsley KG (1978) Gastric secretion of acid in patients with pancreatic disease. Digestion 17:365–369PubMedCrossRefGoogle Scholar
  24. 24.
    Schoenemann J (1977) Therapie der chronischen Pankreatitis. Med Welt 28:463–467PubMedGoogle Scholar
  25. 25.
    Staub JL, Sarles H, Soule JC, Galmiche JP, Capron JP (1981) No effect of Cimetidine on the therapeutic response to oral enzymes in severe pancreatic insufficiency. N Engl J Med 304:1364–1365PubMedGoogle Scholar
  26. 26.
    Worning H (1980) The effect of enzyme substitution in patients with pancreatic insufficiency. Scand J Gastroenterol 15:529–533PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1984

Authors and Affiliations

  • M. Otte

There are no affiliations available

Personalised recommendations