Is General Anaesthesia Detrimental in Severe Acute Head Injury?
Skull base trauma often requires surgical treatment and it is important to consider the timing of surgery. Many surgical factors are involved, but I wish to restrict this lecture to a review of anaesthetic considerations in patients with recent acute brain injury. In essence, does anaesthesia exacerbate brain injury in the first few days after trauma? Table 1 lists headings under which this question will be considered.
KeywordsCerebral Blood Flow Evans Blue Anaesthetic Drug Seizure Threshold Halothane Anaesthesia
Unable to display preview. Download preview PDF.
- McDowall DG, Okuda Y, Heuser D, Keaney NP (1978) Control of cerebral vascular smooth muscle during general anaesthesia. In: Elliott K, O’Connor M (eds) Cerebral Vascular Smooth Muscle and its Control, 257–273 (Ciba Foundation Symposium no. 56) Elsevier/ Exceruta Medica — Amsterdam.Google Scholar
- Miletich DJ, Ivanovich AD, Albrecht RF, Reimann CR, Rosenberg R, McKissie ED (1976) Absence of autoregulation of cerebral blood flow during halothane and enflurane anesthesia. Anesth Analg (Cleve) 55: 100–109.Google Scholar
- Rasmussen MJ, Rosendal T, Overgaard J (1975) Paradoxial responses of regional cerebral blood flow induced by the anaesthetic drug Althesin. In: Harper AM, Jennett WB, Miller JD, Rowan JO (eds). 11. 18–11. 19, Blood Flow and Metabolism in the Brain, Churchill Livingstone, Edinburgh.Google Scholar
- Smith AL, Marque JJ (1975) Anaesthetic effects on experimental cerebral oedema. In: Harper AM, Jennett WB, Miller JD, Rowan JO (eds), p 6.27, Blood Flow and Metabolism in the Brain, Churchill Livingstone, Edinburgh.Google Scholar
- Tweed WA, Overgaard J (1975) Disturbed regulation of CBF after acute brain injury with particular reference to the effects of MIVP and CPP. In: Langfitt TW, McHenry LC, Reivich M, Wollman H (eds). Springer, Berlin.Google Scholar