Inhibition of Aortic Vessel Adenosine Diphosphate Degradation by Cadmium and Mercury

  • G. Togna
  • N. Dolci
  • L. Caprino
Part of the Archives of Toxicology book series (TOXICOLOGY, volume 7)


The effects of cadmium and mercury on ADP breakdown by vessel walls were investigated. These metals reduce the ADP clearance promoted by arterial tissue. This effect could be attributed to the inhibition of vessel wall ADP-ase enzyme, which plays an important role in the genesis of thrombotic phenomena.

Key words

Mercury Cadmium Blood vessel ADP degradation 


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Copyright information

© Springer-Verlag 1984

Authors and Affiliations

  • G. Togna
    • 1
  • N. Dolci
    • 1
  • L. Caprino
    • 2
  1. 1.Institute of HygieneCatholic UniversityRomeItaly
  2. 2.Institute of PharmacologyCatholic UniversityRomeItaly

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