Abstract
When blood vessels are unjured so that they bleed, circulating platelets adhere to the damaged vessel walls and aggregate, so diminishing or arresting the haemorrhage. This interaction between platelets and vessel walls therefore has an easily demonstrable physiological function. There is much clinical and experimental evidence that a deficiency or defect in circulating platelets is associated with “spontaneous” haemorrhages from small vessels. This suggests that platelets are somehow essential for the functional integrity of these vessels, but no mechanism has yet been established.
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Born, G.V.R. (1983). Haemodynamic Influences on Platelets in Haemostasis and Thrombosis. In: Schettler, G., Nerem, R.M., Schmid-Schönbein, H., Mörl, H., Diehm, C. (eds) Fluid Dynamics as a Localizing Factor for Atherosclerosis. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-69085-3_16
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DOI: https://doi.org/10.1007/978-3-642-69085-3_16
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