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Detection of Viral Antigens by Time-Resolved Fluoroimmunoassay

  • Pekka Halonen
  • Olli Meurman
  • Timo Lövgren
  • Ikka Hemmilä
  • Erkkl Soini
Part of the Current Topics in Microbiology and Immunology book series (CT MICROBIOLOGY, volume 104)

Abstract

Highly sensitive immunoassays have proved to be valuable in the diagnosis of viral infections because viral antigens can be directly detected in clinical specimens by these assays. This technology was first widely used in the radioimmunoassay of hepatitis B surface antigen in serum (Ling and Overby 1972) and later applied to the detection of gastroenteritis viruses in stool (Halonen and Meurman 1982). Our group has also developed assays for the detection of seven respiratory viruses in nasopharyngeal secretions (Sarkkinen et al. 1981a-c), and these assays have now been successfully applied on a routine basis in our diagnostic laboratory. Immuno-assays are now widely used in the detection of antiviral antibodies and particularly in the assay of IgM antibodies.

Keywords

Respiratory Syncytial Virus Respiratory Virus Stool Specimen Polystyrene Bead Acute Respiratory Disease 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1983

Authors and Affiliations

  • Pekka Halonen
    • 1
  • Olli Meurman
    • 1
  • Timo Lövgren
    • 2
  • Ikka Hemmilä
    • 2
  • Erkkl Soini
    • 2
  1. 1.Department of VirologyUniversity of TurkuTurku 52Finland
  2. 2.Research Department, Wallac OyTurkuFinland

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