Abstract
The advent of cell fusion techniques for producing monoclonal antibodies has stimulated world-wide effort in the search for antibodies with specificity for neoplastic cells. In parallel, a number of laboratories have attempted to devise ways of attaching cytotoxic agents to antibodies with the aim of generating potent anticancer agents from monoclonal antibodies that exhibit sufficient specificity for cancer cells.
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Thorpe, P.E., Detre, S.I., Mason, D.W., Cumber, A.J., Ross, W.C. (1983). Monoclonal Antibody Therapy: “Model” Experiments with Toxin-Conjugated Antibodies in Mice and Rats. In: Neth, R., Gallo, R.C., Greaves, M.F., Moore, M.A.S., Winkler, K. (eds) Modern Trends in Human Leukemia V. Haematology and Blood Transfusion / Hämatologie und Bluttransfusion, vol 28. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-68761-7_24
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DOI: https://doi.org/10.1007/978-3-642-68761-7_24
Publisher Name: Springer, Berlin, Heidelberg
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