Secretion of Plasminogen Activators by Human Myeloid Leukemic Cells: Modulation and Therapeutic Correlations
Plasminogen activator (PA) synthesis and release are inducible cellular functions [1–7] that are subject to modulation by hormones, drugs, and other pharmacological compounds which act at a genetic level Normal granulocytes synthesize PA [8, 9] and it is known that human cells release, plasminogen activators of two distinct immunochemical types — one similar to urokinase and the other similar to tissue activator [10–13].
KeywordsPlasminogen Activator Acute Myeloid Leukemic Fibrinolytic Activity Phorbol Myristate Acetate Acute Myeloid Leukemic Patient
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