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Control of Involucrin Synthesis During Terminal Differentiation of Human Epidermal Cells in Culture

  • F. M. Watt

Abstract

In the epidermis, cell division takes place in the basal layer. When cells leave this layer they no longer proliferate, but undergo terminal differentiation. Moving through the stratified layers, the cells enlarge progressively and synthesise a range of specialised products. In the outermost cell layers destruction of the nucleus and cytoplasmic organelles occurs, leaving only keratin fibres surrounded by a cross-linked protein envelope.

Keywords

Epidermal Cell Stratum Corneum Basal Layer Terminal Differentiation Cornified Envelope 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1983

Authors and Affiliations

  • F. M. Watt
    • 1
  1. 1.Department of BiologyMassachusetts Institute of TechnologyCambridgeUSA

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