Abstract
Central chemosensitivity is understood as an H+-sensitive structure within the ventral medullary surface layer surrounding the intermediate area (area S) rostrally and caudally (Schlaefke 1981). Elimination of the intermediate area alone is sufficient to abolish the central H+-sensitivity completely. Within this area neurones increase their spontaneous tonic discharge frequency with a decrease of pH, measured on the ventral medullary surface, and may also respond to afferent electrical stimulation of femoral or tibial nerves (Schlaefke 1976a, b, Schlaefke et al. 1979a). Data from in vitro measurements and pharmacological studies led to the assumption that central chemosensitivity is represented by cholinergic synapses and that input from muscle afferents or other sources increases their activity (Dev and Loeschcke 1979, Fukuda and Loeschcke 1979, Spode 1980).
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© 1983 Springer-Verlag Berlin Heidelberg
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Schlaefke, M.E., Burghardt, F. (1983). Training of Central Chemosensitivity in Infants with Sleep Apnea. In: Schläfke, M.E., See, W.R., Koepchen, HP. (eds) Central Neurone Environment and the Control Systems of Breathing and Circulation. Proceedings in Life Sciences. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-68657-3_9
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DOI: https://doi.org/10.1007/978-3-642-68657-3_9
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