A “Panreactive” T Cell Hybridoma Which Produces TCGF Constitutively
We have isolated a T cell line which shows reactivities with irradiated spleen cells of any H-2 haplotype, including self. This “panreactive” T cell line was fused to EL4 and the stable “panreactive” T hybridoma E-M-19-I-1 was shown to help in a “bystander” antibody response to sheep red blood cells (SRC) (1). This “panreactivity” is shown in this paper to be useful as it induces “constitutive” TCGF production in mixtures as well as in fusions with a TCGF-production-inducible T cell hybridoma, BIII/4 (2).
KeywordsSpleen Cell Preceding Article CTLL Cell Thymic Lymphoma Constitutive Production
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