Abstract
We have isolated a T cell line which shows reactivities with irradiated spleen cells of any H-2 haplotype, including self. This “panreactive” T cell line was fused to EL4 and the stable “panreactive” T hybridoma E-M-19-I-1 was shown to help in a “bystander” antibody response to sheep red blood cells (SRC) (1). This “panreactivity” is shown in this paper to be useful as it induces “constitutive” TCGF production in mixtures as well as in fusions with a TCGF-production-inducible T cell hybridoma, BIII/4 (2).
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References
Andersson, J, Melchers, F, Zeuthen, J (1982) A “Panreactive” T cell line and T cell hybridoma: Their function in helping B cells. (This volume.)
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Corbel, C., Andersson, J., Melchers, F., Zeuthen, J. (1982). A “Panreactive” T Cell Hybridoma Which Produces TCGF Constitutively. In: Boehmer, H.V., Haas, W., Köhler, G., Melchers, F., Zeuthen, J. (eds) T Cell Hybridomas. Current Topics in Microbiology and Immunology, vol 100. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-68586-6_20
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DOI: https://doi.org/10.1007/978-3-642-68586-6_20
Publisher Name: Springer, Berlin, Heidelberg
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