Skip to main content

Antibacterial Activity of Aminoglycoside Antibiotics

  • Chapter
Aminoglycoside Antibiotics

Part of the book series: Handbook of Experimental Pharmacology ((HEP,volume 62))

Abstract

The discovery of chemotherapeutic agents was a great moment in the long history of medicine. Yet we are now faced with the problems of drug resistance in bacteria only 50 years after the real start of chemotherapy. The presence of resistance (R) factors and their worldwide spread have caused many problems in medicine, stock farming, and the fish breeding industry. In addition, the prevalence of R factors has broadened our perspective on the role that genetic exchange plays in the natural history of bacterial species.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Davis BD (1950) Nonfiltrability of the agents of genetic recombination in Escherichia coli.J Bacteriol 60:507–508

    PubMed  CAS  Google Scholar 

  • Hashimoto H, Kono K, Mitsuhashi S (1964) Elimination of penicillin resistance of Staphylococcus aureus by treatment with acriflavine. J Bacteriol 88:261–262

    PubMed  CAS  Google Scholar 

  • Inoue M, Mitsuhashi S (1980) The discovery of non-transferable drug resistance (r) plasmids. In: Mitsuhashi S (ed) Bacterial drug resistance. Kodansha, Tokyo, p 19

    Google Scholar 

  • Mitsuhashi S (1960) Drug-resistance of enteric bacteria (in Japanese). Science (Tokyo) 30:628–633

    CAS  Google Scholar 

  • Mitsuhashi S (1977) Epidemiology of bacterial drug resistance. In: Mitsuhashi S (ed) R factordrug resistance plasmid.Japan Scientific Societies Press, University Park Press, Tokyo Baltimore, p 3

    Google Scholar 

  • Mitsuhashi S (1979) Drug resistance plasmids. Molecular Cellular Biochem 26:135–181

    Article  CAS  Google Scholar 

  • Mitsuhashi S (1980) The epidemiology of bacterial resistance. In: Mitsuhashi S (ed) Bacterial drug resistance-R plasmids. Kodansha, Tokyo, p 6

    Google Scholar 

  • Mitsuhashi S, Harada K, Hashimoto H (1960a) Multiple resistance of enteric bacteria and transmission of drug-resistance to other strains by mixed cultivation. Jpn J Exp Med 30:179–184

    PubMed  CAS  Google Scholar 

  • Mitsuhashi S, Hashimoto H, Harada K, Suzuki M, Kameda M, Matsuyama T (1960 b) Multiple resistance of S.flexneri 3 a and E. coli isolated from the epidemy in Gunma Prefecture (in Japanese). Jpn J Bacteriol 15:844–848

    Article  Google Scholar 

  • Mitsuhashi S, Harada K, Kameda M (1960 c) Elimination of transmissible drug-resistance by treatment with acriflavine (in Japanese). Tokyo Iji Shinshi 77:462

    Google Scholar 

  • Mitsuhashi S, Harada K, Kameda M (1961) Elimination of transmissible drug-resistanceby treatment with acriflavine. Nature 189:947

    Article  PubMed  CAS  Google Scholar 

  • Mitsuhashi S, Morimura M, Kono K, Oshima H (1963) Elimination of drug resistance ofStaphylococcus aureus by treatment with acriflavine. J Bacteriol 86:162–163

    PubMed  CAS  Google Scholar 

  • Mitsuhashi S, Hashimoto H, Kono M, Morimura M (1965) Joint elimination and joint transduction of the determinants of penicillinase production and resistance to macrolide antibiotics. J Bacteriol 89:988–992

    PubMed  CAS  Google Scholar 

  • Mitsuhashi S, Inoue M, Kawabe H, Oshima H, Okubo T (1973) Genetic and biochemical studies of drug resistance in staphylococci. In: Jeljaszewicz J (ed) Staphylococci and staphylococcal infections. Karger, Basel, p 144

    Google Scholar 

  • Mitsuhashi S, Inoue M, Oshima H, Okubo T, Saito T (1976) Epidemiologic and genetic studies of drug resistance in staphylococci. In: Jeljaszewicz J (ed) Staphylococci and staphylococcal diseases. Fischer, Stuttgart New York, p 255

    Google Scholar 

  • Mitsuhashi S, Kawabe H, Nagate T, Inoue K (1977 a) Evolutionary process of the formation of multiple resistance plasmid. In: Drews J, Hoegenauer G (eds) Topics in infectious diseases, vol 2, Springer, Berlin Heidelberg New York, p 165

    Google Scholar 

  • Nakae M, Inoue M, Mitsuhashi S (1975) Artificial elimination of drug resistance from group A beta-hemolytics streptococci. Antimicrob Agents Chemother 7:719–720

    PubMed  CAS  Google Scholar 

  • Novick RP (1963) Analysis by transduction of mutation affecting penicillinase formation in Staphylococcus aureus. J Gen Microbiol 33:121–136

    PubMed  CAS  Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1982 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Mitsuhashi, S. (1982). Antibacterial Activity of Aminoglycoside Antibiotics. In: Umezawa, H., Hooper, I.R. (eds) Aminoglycoside Antibiotics. Handbook of Experimental Pharmacology, vol 62. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-68579-8_4

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-68579-8_4

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-68581-1

  • Online ISBN: 978-3-642-68579-8

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics