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Septischer Schock: Prophylaxe und Therapie

  • Conference paper
Notfalltherapie

Part of the book series: Interdisziplinäre Gastroenterologie ((GASTROENTEROLOG))

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Zusammenfassung

Bei mehr als einem Drittel der gastrointestinalen Infektionen sind intermittierend Bacteriämien nachweisbar. Wichtigste Eintrittspforte sind die Gallenwege [13, 58]. Als Erreger finden sich vor allem Anaerobier, aerobe Keime sind seltener; oft bestehen jedoch Mischinfektionen [10, 17]. Häufigste, in Blutkulturen nachweisbare aerobe Keime sind E. coli, unter den anaeroben Erregern überwiegend die Bacteroides species [31,35].

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Literatur

  1. Abernathy RS, Fields BT, Monson TP, Nolan ChM (1979) Prophylaxis of infection with antimicrobial therapy. J Arkansas Med Soc 76:55–62

    PubMed  CAS  Google Scholar 

  2. Bartlett JG (1979) Antibiotic — associated Colitis. Clin Gastroenterol 8:783

    PubMed  CAS  Google Scholar 

  3. Beller FK, Douglas GW (1973) Thrombocytopenia indicating gram-negative infection and endotoxinemia. Obstet Gynecol 41:521

    PubMed  CAS  Google Scholar 

  4. Bocking JK, Sibbald WJ, Holliday RL, Scott S, Viidik T (1979) Plasma catecholamine levels and pulmonary dysfunction in sepsis. Surg Gynecol Obstet 148:715–719

    PubMed  CAS  Google Scholar 

  5. Boxerbaum B (1974) Antimicrobial drugs for treatment of infections caused by aerobic gramnegative bacilli. Med Clin North Am 58:519

    PubMed  CAS  Google Scholar 

  6. Braude AI, Ziegler EJ, McCutchan JA (1978) Antiserum treatment of gram-negative bacteremia. Schweiz Med Wochenschr 108:1872–1876

    PubMed  CAS  Google Scholar 

  7. Brooks GF, Pribble AH, Beaty HN (1973) Early diagnosis of bacteremia by buffy-coat examination. Arch Intern Med 132:673

    Article  PubMed  CAS  Google Scholar 

  8. Burke JF (1977) Preventing bacterial infection by coordinating antibiotic and host activity:A time dependent relationship. South Med J [Suppl] 70:24

    Google Scholar 

  9. Chodak GW, Plaut ME (1977) Use of systemic antibiotics for prophylaxis in surgery. A critical review. Arch Surg 112:326

    PubMed  CAS  Google Scholar 

  10. Chow AW, Guze LB (1974) Bacteroidycea bacteremia:Clinical experience with 112 patients. Medicine (Baltimore) 53:93

    CAS  Google Scholar 

  11. Corrigan JJ (1977) Heparin therapy in bacterial septicemia. J Pediatr 91:695

    Article  PubMed  Google Scholar 

  12. Downing R, McLeish AR, Burdon DW (1977) Duration of systemic prophylactic antibiotic cover against anaerobic sepsis in bowel surgery. Dis Colon Rectum 20:401

    Article  PubMed  CAS  Google Scholar 

  13. DuPont HL, Spink WW (1969) Infections due to gram-negative organisms:an analysis of 860 patients with bacteremia at the university of Minnesota Medical Center, 1958–1966. Medicine (Baltimore) 48:307–332

    Article  CAS  Google Scholar 

  14. Elin RJ, Robinson RA, Levine AS, Wolff SM (1975) Lack of clinical usefullness of the limulus test in the diagnosis of endotoxinemia. N Engl J Med 11:521

    Article  Google Scholar 

  15. Fass RJ, Ruiz DE, Gardener WG, Rotilie CA (1977) Clindamycin and Gentamycin for aerobic and anaerobic sepsis. Arch Intern Med 137:28–38

    Article  PubMed  CAS  Google Scholar 

  16. Fearon DT, Ruddy S, Schur PH (1975) Activation of the properdin pathway of complement in patients with gramnegative bacteremia. N Engl J Med 292:937

    Article  PubMed  CAS  Google Scholar 

  17. Finegold SM (1977) Abdominal and perineal infections. Anaerobic bacteria in human disease. Academic Press, New York, p 257

    Google Scholar 

  18. Fletcher JR, Rawell PW (1979) Indomethacin improves survival after endotoxin in baboons. Second annual conference on shock. Colonial Williamsburg, Virginia

    Google Scholar 

  19. Forgacs P (1979) Treatment of septic shock. Med Clin North Am 63:465–471

    PubMed  CAS  Google Scholar 

  20. Gersmeyer EF, Yasargil EC (1978) Schock und hypotone Kreislaufstörungen. Thieme, Stuttgart

    Google Scholar 

  21. Gorbach SL, Bartlett JG (1974) Anaerobic infections. N Engl J Med 290:1177, 1237, 1289

    Article  PubMed  CAS  Google Scholar 

  22. Graeff H, Kuhn W, Zander J (1974) Sepsis in der Geburtshilfe. Therapiewoche 24:6173

    Google Scholar 

  23. Hassen A (1973) Gram-negative bacteremic shock. Med Clin North Am 57:1403–1415

    PubMed  CAS  Google Scholar 

  24. Hau T, Nelson RD, Fiegel VD (1977) Mechanisms of the adjuvant action of hemoglobin in experimental Peritonitis. — Influence of hemoglobin on human leukocyte Chemotaxis in vitro. J Surg Res 22:174

    Article  PubMed  CAS  Google Scholar 

  25. Herzig RH, Herzig GP, Graw RG (1977) Successfull granulocyte transfusion therapy for gram-negative septicemia. N Engl J Med 296:701

    Article  PubMed  CAS  Google Scholar 

  26. Hughes WT, Kuhn S, Chaudhary S (1977) Successfull chemoprophylaxis of pneumocystis carinii pneumonitis. N Engl J Med 297:1419

    Article  PubMed  CAS  Google Scholar 

  27. Keighley MRB, Arabi Y, Matheson D, Alexander-Williams J (1978) Aspects of preventing sepsis in colo-rectal surgery:results of recent clinical trials. J Antimicrob Chemother 4S:33–38

    PubMed  Google Scholar 

  28. Keighley M, Baddeley R, Burdon D (1975) A controlled trial of parenteral prophylactic gentamycin therapy in biliary surgery. B J Surg 62:275

    Article  CAS  Google Scholar 

  29. Kügler S, Hagemann J, Monti R (1976) Lokalisationsdiagnostik von Abszessen und Entzündungen mit Technetium 99. Dtsch Med Wochenschr 31:1162

    Article  Google Scholar 

  30. Kvale PA, Ranga V, Kopacz M (1977) Pulmonary resection. South Med J [Suppl] 70:64

    Google Scholar 

  31. Landesman SH, Gorbach SL (1978) Gram negative sepsis and shock. Orthop Clin North Am 9:611–625

    PubMed  CAS  Google Scholar 

  32. Lefer AM (1974) Myocardial depressant factor and circulatory shock. Klin Wochenschr 52:358

    Article  PubMed  CAS  Google Scholar 

  33. Levison ME, Santoro J, Bran JL (1977) In vitro activity and clinical efficacy of Clindamycin in the treatment of infections due to anaerobic bacteria. J Infect Dis 135:49

    Article  Google Scholar 

  34. Littenberg RL, Taketa RM, Alazraki SE (1973) Gallium 67 for localisation of septic lesions. Ann Intern Med 79:403

    PubMed  CAS  Google Scholar 

  35. MacLean LD, Mulligan WG, McLean APH, Duff JH (1967) Patterns of septic shock in man a detailed study of 56 patients. Ann Surg 166:543–562

    Article  PubMed  CAS  Google Scholar 

  36. McHenry MC, Hawk WA (1974) Bacteremia caused by gram-negative bacilli. Med Clin North Am 58:623–638

    PubMed  CAS  Google Scholar 

  37. McHenry CM, Gavan TL, Hawk WA, Ma C, Berrettoni JN (1975) Gram-negative bacteremia:variable clinical course and useful prognostic factors. Cleve Clin Q 42:15–32

    PubMed  CAS  Google Scholar 

  38. Moellering RC, Kunz LJ, Poitras JW (1977) Microbiologic basis for the rational use of prophylactic antibiotics. South Med J [Suppl] 70:8

    Google Scholar 

  39. Moody MR, Young VM, Kenton DM (1972) Pseudomonas aeruginosa in a center for cancer research I Distribution of intraspecies types from human and environmental sources. J Infect Dis 125:95

    Article  PubMed  CAS  Google Scholar 

  40. Neu HC (1977) Clinical pharmakokinetics in preventive antimicrobial therapy. South Med J [Suppl] 70:14

    CAS  Google Scholar 

  41. Nolan JP (1975) The role of endotoxin in liver injury. Gastroenterology 69:1346

    PubMed  CAS  Google Scholar 

  42. Onderdonk AB, Bartlett JG, Louie T (1976) Microbial synergy in experimental intraabdominal abscess. Infect Immun 13:22

    PubMed  CAS  Google Scholar 

  43. Orskov F, Orskov I (1975) Escherichia coli O:H serotypes isolated from human blood. Acta Pathol Microbiol Scand 83:595

    CAS  Google Scholar 

  44. Peters WP, Johnson MW, Friedman PA, Mitch WE (1981) Pressor effect of naloxone in septic shock. Lancet 7:529

    Article  Google Scholar 

  45. Polk H, Lopez-Mayor J (1969) Post-operative wound infections:A prophylactic study of determinant factors and prevention. Surg 66:97

    Google Scholar 

  46. Rapkin RH (1979) Chemoprophylaxis of bacterial infections. J Med Soc N J 76:446–450

    PubMed  CAS  Google Scholar 

  47. Regnier B, Safran D, Carlet J, Teisseire B (1979) Comparative haemodynamic effects of dopamine and dobutamine in septic shock. Intensive Care Med 5:115–120

    Article  PubMed  CAS  Google Scholar 

  48. Riedler GF (1972) Thrombozytenzahl, weißes Blutbild und anorganisches Phosphat:drei wertvolle Kriterien zur Diagnose einer Sepsis. Schweiz Med Wochenschr 102:497

    PubMed  CAS  Google Scholar 

  49. Schumer W (1976) Steroids in the treatment of clinical septic shock. Ann Surg 184:33–34

    Article  Google Scholar 

  50. Shine KI, Kuhn M, Young LS, Tillisch JH (1980) Aspects of the management of shock. UCLA conference. Ann Intern Med 93:723

    PubMed  CAS  Google Scholar 

  51. Smith CR, Lipsky JJ, Laskin OL (1980) Double blind comparison of the nephrotoxicity and auditory toxicity of gentamycin and tobramycin. N Engl J Med 302:1106

    Article  PubMed  CAS  Google Scholar 

  52. Stone HH, Haney BB, Kolb LD, Geheber CE, Hooper CA (1979) Prophylactic and preventive antibiotic therapy. Timing, duratio and economics. Ann Surg 189:691–699

    Article  PubMed  CAS  Google Scholar 

  53. Stone HH, Hooper CA, Kolb LD (1976) Antibiotic prophylaxis in gastric, biliary and colonic surgery. Ann Surg 184:443

    Article  PubMed  CAS  Google Scholar 

  54. Stone HH, Kolb LD, Geheber CE (1975) Incidence and significance of intraperitoneal anaerobic bacteria. Ann Surg 181:705–715

    Article  PubMed  CAS  Google Scholar 

  55. Stone HH, Martin JD (1972) Synergistic necrotizing cellulitis. Ann Surg 175:702

    Article  PubMed  CAS  Google Scholar 

  56. Straub PW (1979) Intravasale Gerinnung:Symptom oder Krankheit. Schweiz Med Wochenschr 109:1351

    PubMed  CAS  Google Scholar 

  57. Sutter VL, Finegold SM (1976) Susceptibility of anaerobic bacteria to 23 antimicrobial agents. Antimicrob Agents Chemother 10:736

    PubMed  CAS  Google Scholar 

  58. Swenson RM, Lorber B, Michaelson TC (1974) The bacteriology of intraabdominal infections. Arch Surg 109:398

    PubMed  CAS  Google Scholar 

  59. Tedesco FJ (1980) Antibiotic-associated pseudomembranous Colitis. Compr Ther 6:15

    PubMed  CAS  Google Scholar 

  60. Ulevitch RJ, Cochrane CG (1978) Role of complement in lethal bacterial lipopolysaccharid induced hypotensive and coagulative changes. Infect Immun 20:204

    Google Scholar 

  61. Verklin RM, Mandell GL (1977) Alteration of effectiveness of antibiotics by anaerobiosis. J Lab Clin Med 89:65

    PubMed  CAS  Google Scholar 

  62. Washington JA (1975) Blood cultures. Principles and techniques. Mayo Clin Proc 50:91–98

    PubMed  Google Scholar 

  63. Wolff S (1973) Biological effects of bacterial endotoxins in man. J Infect Dis [Suppl] 128:259

    Google Scholar 

  64. Young LS, Martin W Jr, Meyer RD (1977) Gram-negative rod bacteremia:Microbiologic, immunologic and therapeutic considerations. Ann Intern Med 86:456

    PubMed  CAS  Google Scholar 

  65. Young LS, Meyer RD, Armstrong D (1973) Pseudomonas aeruginosa Vaccine in cancer patients. Ann Intern Med 79:518

    PubMed  CAS  Google Scholar 

  66. Young LS, Stevens P, Ingram J (1975) Functional role of antibody against “core” glycolipid of Enterobacteriaceae. J Clin Invest 56:850

    Article  PubMed  CAS  Google Scholar 

  67. Zieve PD, Haghshenass M, Blanks M, Krevans JR (1968) Vacuolisation of the neutrophil. Arch Intern Med 18:356

    Google Scholar 

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Authors
  1. M. Spiegel
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Editors and Affiliations

  1. Klinik und Poliklinik für Allgemeinchirurgie, der Georg-August-Universität Göttingen, Robert-Koch-Straße 40, D-3400, Göttingen, Germany

    Jörg Rüdiger Siewert

  2. Medizinische Klinik, Stadtspital Triemli, Birmendorferstraße 497, CH-8063, Zürich, Switzerland

    André Louis Blum

  3. Abteilung für Allgemeine Chirurgie mit Poliklinik, Chirurgische Universitätsklinik, Hugstetterstraße 55, D-7800, Freiburg, Germany

    Eduard H. Farthmann

  4. Abteilung Gastroenterologie und Stoffwechsel, Medizinische Universitätsklinik, Robert-Koch-Straße 40, D-3400, Göttingen, Germany

    Paul G. Lankisch

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© 1982 Springer-Verlag Berlin Heidelberg

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Spiegel, M. (1982). Septischer Schock: Prophylaxe und Therapie. In: Siewert, J.R., Blum, A.L., Farthmann, E.H., Lankisch, P.G. (eds) Notfalltherapie. Interdisziplinäre Gastroenterologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-68497-5_4

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  • DOI: https://doi.org/10.1007/978-3-642-68497-5_4

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-68498-2

  • Online ISBN: 978-3-642-68497-5

  • eBook Packages: Springer Book Archive

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