Amines: Histamine

Part of the Handbook of Experimental Pharmacology book series (HEP, volume 59 / 2)


Physiologic roles of histamine have not yet been clarified. Its distribution in the gastrointestinal tract is consistent with the idea that it has a function in secretion rather than in motility, but there are many important factors which cannot be disregarded: the turnover rate of histamine, the number and susceptibility of receptors at the specific targets, the interaction with other humoral and nervous mediators, etc. Of course, detailed consideration of histamine distribution, synthesis, and metabolism is beyond the scope of this review.


Gastric Emptying Lower Esophageal Sphincter Longitudinal Muscle Circular Muscle Histamine Receptor 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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