Abstract
The architectural and junctional specializations of astrocytes, oligodendrocytes, and Schwann cells are reviewed in the context of the general features of epithelia and tissue compartments. Glial cells form microvilli, secretory vesicles, and several types of cell junctions. Also, certain non-junctional membrane specializations have been revealed by the freeze-fracture method. Most of the membrane specializations are not randomly distributed, but appear to be related to local peculiarities in the cell’s microenvironment. The most conspicuous of these are found at Ranvier nodes of myelinated fibers and at the interface between different tissue compartments. The individual specializations are briefly reviewed. Possible relations to certain pathological processes that may affect astrocytic orthogonal assemblies, gap junctions, tight junctions, and nodal and paranodal specializations are stressed.
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© 1982 Dr. S. Bernhard, Dahlem Konferenzen, Berlin
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Mugnaini, E. (1982). Membrane Specializations in Neuroglial Cells and at Neuron-Glia Contacts. In: Sears, T.A. (eds) Neuronal-glial Cell Interrelationships. Dahlem Workshop Reports Life Sciences Research Report, vol 20. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-68466-1_5
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DOI: https://doi.org/10.1007/978-3-642-68466-1_5
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