Abstract
Immediately after its publication the Kiel classification of non-Hodgkin lymphomas (NHL) [10,15] attracted the interest not only of pathologists but also of clinicians. In order to analyze its clinical applicability and prognostic value which are considered to be the most crucial points for the practical use of a new histopathologic system, in West Germany and Austria several internists and radiotherapists formed a cooperative multi-center study group. This so-called Kiel Lymphoma Study Group first started a retrospective investigation evaluating data from 405 patients [4, 5, 23]. Encouraging results of this analysis led the same group in 1975 to initiate a more detailed prospective study [3]. After a period of 5 years, in October 1980 when registration of new patients was closed, more than 1000 patients from 20 hospitals had entered the study.
Supported by the Deutsche Krebshilfe e. V., Bonn, and the Deutsche Forschungsgemeinschaft, Bonn-Bad Godesberg, Sonderforschungsbereich 102, Essen
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Bagley CM, DeVita VT, Berard CW, Canellos GP (1972) Advanced lymphosarcoma: Intensive cyclical combination chemotherapy with cyclophosphamide, vincristine and prednisone. Ann Intern Med 76: 227–234
Bonadonna G, De Lena M, Lattuada A, Milani F, Monfardini S, Beretta G (1975) Combination chemotherapy and radiotherapy in non-Hodgkin’s lymphomata. Br J Cancer [Suppl II] 31: 481–488
Brittinger G (1978) Outline of a prospective multicentric study on the clinical significance of the Kiel classification of non-Hodgkin’s lymphomas. Recent Results Cancer Res 65: 195–199
Brittinger G, Bartels H, Bremer K, Dühmke E, Gunzer U, König E, Stein H (1976) Klinik der malignen Non-Hodgkin-Lymphome entsprechend der Kiel-Klassifikation: Centrocytisches Lymphom, centroblastisch-centrocytisches Lymphom, lymphoblastisches Lymphom, immuno- blastisches Lymphom. In: Löffler H (ed) Maligne Lymphome und monoklonale Gammopathien. Haematol Bluttransfus 18: 211–223
Brittinger G, Battels H, Bremer K, Burger A, Dühmke E, Gunzer U et al. (1977) Retrospektive Untersuchungen zur klinischen Bedeutung der Kiel-Klassifikation der malignen Non-Hodgkin-Lymphome. Strahlentherapie 153: 222–228
Brittinger G, Schmalhorst U, Bartels H, Bremer K, Brunswicker F, Burger A et al. (Kiel Lymphoma Study Group) (1979) Chemotherapy of non-Hodgkin’s lymphomas — Indications and results. In: Crowther DG (ed) Leukemia and non-Hodgkin Lymphoma. Pergamon Press, Oxford New York Toronto Sydney Paris Frankfurt: Advances in Medical Oncology, Research and Education, vol VII, pp 229–241
Brittinger G, Schmalhorst U, Bartels H, Fülle HH, Gerhartz H, Gremmel H, et al. (Kiel Lymphoma Study Group) (to be published) Principles and present status of a prospective multicenter study on the clinical relevance of the Kiel classification. Blut
Carbone PP, Kaplan HS, Musshoff K, Smithers DW, Tubiana M (1971) Report of the committee on Hodgkin’s disease staging classification. Cancer Res 31: 1860–1861
DeVita VT jr, Serpick A, Carbone PP (1970) Combination chemotherapy in the treatment of advanced Hodgkin’s disease. Ann Intern Med 73: 881–895
Gerard-Marchant R, Hamlin I, Lennert K, Rilke F, Stansfeld AG, van Unnik JAM (1974) Classification of non-Hodgkin’s lymphomas. Lancet II: 406–408
Han T, Ezdinli EZ, Shimaoka K, Desai DV (1973) Chlorambucil vs combined chlorambucil-corticosteroid therapy in chronic lymphocytic leukemia. Cancer 31: 502–508
Heinz R, Stacher A, Pralle H, Theml H, Brunswicker F, Burkert M, et al. (Kiel Lymphoma Study Group) (to be published) Lymphoplasmacytic/lymphoplasmacytoid lymphoma: A clinical entity distinct from chronic lymphocytic leukaemia? Blut
Knospe WH, Loeb V jr, Huguley CM jr (1974) Bi-weekly chlorambucil treatment of chronic lymphocytic leukemia. Cancer 33: 555–562
König E, Bartels H, Bremer K, Burger- Schüler A, Common H, Dühmke E, Engelhard M, et al. (Kiel Lymphoma Study Group) (to be published) Germinal center cell lymphomas: Prognostic significance of their histopathological differentiation. Blut
Lennert K (1978) Malignant lymphomas other than Hodgkin’s disease. In: Uehlinger E (ed) Lymphknoten, Diagnostik in Schnitt und Ausstrich. Springer, Berlin Heidelberg New York (Handbuch der speziellen pathologischen Anatomie und Histologic, vol 1, part 3B )
McKelvey EM, Gottlieb JA, Wilson HE, Haut A, Talley RW, Stephens R, et al. (1976) Hydroxyldaunomycin (adriamycin) combination chemotherapy in malignant lymphoma. Cancer 38: 1484–1493
Meusers P, Bartels H, Brittinger G, Common H, Dühmke E, Fülle HH, Gunzer U, et al. (Kiel Lymphoma Study Group) (1979) Heterogeneity of diffuse “histiocytic” lymphoma according to the Kiel classification. N Engl J Med 301: 384
Musshoff K, Schmidt-Vollmer H (1975) Prognosis of non-Hodgkin’s lymphomas with special emphasis on the staging classification. Z Krebsforsch 83: 323–341
Portlock CS, Rosenberg SA (1977) Chemotherapy of the non-Hodgkin’s lymphomas: The Stanford experience. Cancer Treat Rep 61: 1049–1055
Rosenberg SA (1979) Non-Hodgkin’s lymphoma — Selection of treatment on the basis of histologic type. N Engl J Med 301: 924–928
Rosenberg SA, Kaplan HS (1975) Clinical trials in the non-Hodgkin’s lymphomata at Stanford University. Experimental design and preliminary results. Br J Cancer [Suppl II] 31: 456–464
Schmalhorst U, Bartels H, Boll I, Burger-Schüler A, Common H, Fülle HH, Graubner M, et al. (Kiel Lymphoma Study Group) (to be published) Clinical and prognostic heterogeneity of non-Hodgkin lymphomas of high-grade malignancy. Blut
Stacher A, Waldner R, Theml H (1976) Klinik der malignen Non-Hodgkin-Lymphome entsprechend der Kieler Klassifikation: Lymphoplasmozytoides Lymphom (LPL) and chronisch lymphatische Leukämie (CLL). Hämatol Bluttransfus 18: 199–209
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1982 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Brittinger, G. (1982). Kiel Lymphoma Study Group. In: Goos, M., Christophers, E. (eds) Lymphoproliferative Diseases of the Skin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-68363-3_31
Download citation
DOI: https://doi.org/10.1007/978-3-642-68363-3_31
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-11222-8
Online ISBN: 978-3-642-68363-3
eBook Packages: Springer Book Archive