Variant Angina: The Role of Thromboxane A2 with Observations on the Importance of Study Design

  • G. C. Friesinger
  • R. M. S. Robertson
  • D. Robertson
  • G. Fitzgerald
  • J. Roberts
  • R. Moss
  • J. Oates
Conference paper


The principal focus of this symposium is on the relief of acute coronary artery obstruction, but it seems appropriate to be concerned with the mechanisms by which an acute occlusion may occur. Data are extremely fragmentary and incomplete concerning events immediately preceding and responsible for acute myocardial infarction, although the evidence that they result in acute obstruction in a large portion of patients now seems convincing.


Platelet Aggregation Coronary Sinus Coronary Spasm Coronary Artery Spasm Placebo Period 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1982

Authors and Affiliations

  • G. C. Friesinger
    • 1
  • R. M. S. Robertson
    • 1
  • D. Robertson
    • 1
  • G. Fitzgerald
    • 1
  • J. Roberts
    • 1
  • R. Moss
    • 1
  • J. Oates
    • 1
  1. 1.Divisions of Cardiology and Clinical PharmacologyVanderbilt Medical SchoolNashvilleUSA

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