Summary
Several studies demonstrated that the direct cardiodepressant effect is without significance for the therapeutic actions and the side effects of beta receptor blocking agents. In hypertension and angina pectoris, the disease states where beta blockers are given most frequently, sympathomimetic activity and cardioselectivity don’t play a role as far as the therapeutical efficacy is concerned. In hyperthyroidism, migraine and in cardiac arrythmias, where slowing of A-V conduction is desired, blockers without sympathomimetic effect are preferable. In patients with obstructive airways disease, a cardioselective antagonist should be used if treatment with a beta blocker is considered at all. In diabetic patients treated with insulin one would prefer a cardioselective beta-receptor antagonist.
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© 1981 Springer-Verlag, Berlin, Heidelberg
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Rahn, K.H. (1981). Different Types of Beta-Blocking Agents: Therapeutic Implications. In: Delius, W., Gerlach, E., Grobecker, H., Kübler, W. (eds) Catecholamines and the Heart. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-68321-3_26
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DOI: https://doi.org/10.1007/978-3-642-68321-3_26
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