Intrathecally Applied Morphine for Treatment of Postoperative and Chronic Pain

  • B. Kossmann
  • A. Driessen
  • H. H. Mehrkens
  • W. Dick
Part of the Anaesthesiologie und Intensivmedizin Anaesthesiology and Intensive Care Medicine book series (A+I, volume 144)


Eleven patients suffering from metastases to the lumbar spine or pelvis received multiple intrathecal injections of 0.5–1.5 mg morphine. The first injection produced pain relief for 18–84 hours. A hypoalgesia following the intrathecal injection persisted up to 4 days. No change in blood pressure or heart rate was noted.


Cancer Pain Intrathecal Injection Epidural Morphine Epidural Injection Intrathecal Morphine 
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    Behar M, Magora F, Olshwang D, Davidson JT (1979) Epidural Morphine in treatment of pain. Lancet 1:527PubMedCrossRefGoogle Scholar
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    Davies GK, Tohurst-Cleaver CL, James TL (1980) CNS depression from intrathecal morphine. Anesthesiology 52:280PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1982

Authors and Affiliations

  • B. Kossmann
  • A. Driessen
  • H. H. Mehrkens
  • W. Dick

There are no affiliations available

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