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The Control of Postoperative Pain by Thoracic Fentanyl Epidural and its Effect Upon the Stress Response

  • E. A. Welchew
  • J. A. Thornton
Part of the Anaesthesiologie und Intensivmedizin Anaesthesiology and Intensive Care Medicine book series (A+I, volume 144)

Summary

Patients scheduled for elective upper abdominal surgery were divided into two groups. Group 1 received preoperative diazepam and a thoracic epidural catheter through which was administered 200 μg in saline. Postoperatively, epidural infusion of fentanyl (approximately 66 μg/h) was maintained. Group 2 received pre- and postoperative medication with papaveretum i.m. All patients were anaesthesized with nitrous oxide and halothane. Postoperatively, Group 1 showed low pain and sedation scores though higher nausea scores than those observed in Group 2. Postoperative respiratory function was significantly better urine output and nasogastric output was significantly greatry depression were observed.

Keywords

Epidural Analgesia Sedation Score Epidural Fentanyl Respiratory Function Test Nausea Score 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Yaksh TL, Rudy TA (1976) Analgesia mediated by a direct action of narcotics. Science 192:1352CrossRefGoogle Scholar
  2. 2.
    Yaksh TL (1978) Analgesic action of intrathecal opiates in cat and primate. Brain Res 153:205PubMedCrossRefGoogle Scholar
  3. 3.
    Yaksh TL, Henry JL (1978) Antinociceptive effects of intrathecally administered β endorphin in the rat and cat Can J Physiol Pharmacol 56:754PubMedCrossRefGoogle Scholar
  4. 4.
    Yaksh TL, Rudy TA (1976) Analgesia mediated by a direct spinal action of narcotics. Science 192:1352CrossRefGoogle Scholar
  5. 5.
    Behar M, Olshwang D, Magora F, Davidson JT (1979) Epidural morphine in the treatment of pain. Lancet 1:527PubMedCrossRefGoogle Scholar
  6. 6.
    Samii K, Feret J, Karari A, Viars P (1979) Selective spinal analgesia. Lancet 1:1142PubMedGoogle Scholar
  7. 7.
    Wang JK, Nauss LA, Thomas JE (1979) Pain relief by intrathecally applied morphine in man. Anesthesiology 50:149PubMedCrossRefGoogle Scholar
  8. 8.
    Wolfe MJ, Nicholas ADG (1979) Selective epidural analgesia. Lancet 2:150PubMedCrossRefGoogle Scholar
  9. 9.
    Wolfe MJ, Davies GK (1980) Analgesic action of extradural Fentanyl. Br J Anaesth 52:357PubMedCrossRefGoogle Scholar
  10. 10.
    Kehlet H (1978) Influence of epidural analgesia on the endocrine-metabolic response to surgery. Acta Anaesth Scand 70:39Google Scholar
  11. 11.
    Cooper GM, Holdcroft A, Hall GM, Alaghband-Zadeh J (1979) Epidural analgesia and the metabolic response to surgery. Canad Anaesth Soc J 26:382CrossRefGoogle Scholar
  12. 12.
    Hall GM, Young C, Holdcroft A, Alaghband-Zadeh J (1978) Substrate mobilization during surgery. Anaesthesia 33:924PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1982

Authors and Affiliations

  • E. A. Welchew
  • J. A. Thornton

There are no affiliations available

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