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Pain Relief with Morphine, Applied Intrathecally or Epidural

  • J. Sarubin
  • E. Gebert
Chapter
Part of the Anaesthesiologie und Intensivmedizin Anaesthesiology and Intensive Care Medicine book series (A+I, volume 144)

Summary

To examine the effects of intrathecal and epidural opiates, three groups of patients were examined. Group I consisted of patients suffering from chronic cancer and multiple rib fractures and received intrathecal morphine (1 mg/2 ml in 5% glucose, intrathecal). Group II consisted of patients who underwent abdominal surgery and received intrathecal morphine (1 to 2 mg/2 ml glucose) (before anaesthesia). Group III was a second postoperative group which received epidural morphine (4 mg/10 to 20 ml saline). Group I patients showed a mean pain relief of 25 hrs which began approximately 20 min after the injection. In this group, no side effects including respiratory depression were observed. Group II showed a mean postoperative pain relief of 33 hrs. In this group, three patients showed significant respiratory depression which was naloxone antagonizable. Group III showed a mean postoperative pain relief of 16 hours. No respiratory depression was observed.

Keywords

Pain Relief Respiratory Depression Epidural Morphine Intrathecal Morphine Postoperative Pain Relief 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1982

Authors and Affiliations

  • J. Sarubin
  • E. Gebert

There are no affiliations available

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