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Effects of Cardiac Glycosides on Central Nervous System

  • Chapter
Cardiac Glycosides

Part of the book series: Handbook of Experimental Pharmacology ((HEP,volume 56 / 1))

Abstract

As compared with their cardiac side effects, the central nervous system (CNS) side effects caused by the therapeutic use of cardiac glycosides are of relatively minor significance. This difference is partly due to the preferential concentration of the glycosides in the myocardium; the levels reached in the CNS are much lower. Furthermore, such neurologic side effects as do occur are more or less subjective in nature and are not measurable. This is true even of the commonest central nervous side effect, namely nausea and vomiting. Even in cases of unquestionable digitalis poisoning, where the diagnosis has been confirmed by serum assays, the frequency of these symptoms is the subject of widely varying estimates by different authors — from 61% by one group to 25% by another (Beller et al., 1974; Haasis et al., 1975).

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Authors
  1. H. F. Benthe
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Editors and Affiliations

  1. Instituts für Pharmakologie, Universität Düsseldorf, Moorenstrasse 5, D-4000, Düsseldorf, Germany

    Kurt Greeff (Direktor) (Direktor)

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© 1981 Springer-Verlag Berlin Heidelberg

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Benthe, H.F. (1981). Effects of Cardiac Glycosides on Central Nervous System. In: Greeff, K. (eds) Cardiac Glycosides. Handbook of Experimental Pharmacology, vol 56 / 1. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-68163-9_21

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  • DOI: https://doi.org/10.1007/978-3-642-68163-9_21

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-68165-3

  • Online ISBN: 978-3-642-68163-9

  • eBook Packages: Springer Book Archive

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