Skip to main content
SpringerLink
Log in

Study of Pituitary Secretion Using the Thyrotrophin-Releasing Hormone Test in Uremic Prepubertal Children

  • Conference paper
Renal Insufficiency in Children

Abstract

Endocrine abnormalities are one of the hazards in the rehabilitation of patients with chronic renal failure (CRF) but little is known at present about hormonal changes in uremic children. The aims of this study were to investigate the hypophyseal function using the thyrotrophin-releasing hormone (TRH) test in prepubertal children and to evaluate the influence of both chronic uremia and regular dialytic treatment. We emphasize that all children were prepubertal, P-j stage according to Tanner’s score.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Giusti M, Bolognesi F, Para, z. zi F, Mortala, R, Giordano G (1978) Ritmo sonn-veglia e tassi integrati di alcuni ormoni ipofisari in soggetti in crisi puberale. Minerva Endocrinologica 3: 71

    CAS  Google Scholar 

  2. Czernichow P, Dauzet MC, Broyer M, Rappaport R (1976) Abnormal TSH, PRL, and GH response to TSH releasing factor in chronic renal failure. J Clin Endocrinol Metab 43: 630

    Article  PubMed  CAS  Google Scholar 

  3. Cowden EA, Ratcliffe WA, Ratcliffe JG, Dobbie JW, Kennedy AC (1978) Hyperprolactinaemia in renal disease. Clin Endocrinol (Oxf) 2: 241

    Article  Google Scholar 

  4. Lim VS, Kathpalia S, Frohman LA (1979) Hyperprolactinemia and impaired pituitary response to suppression and stimulation in chronic renal failure: reversal after renal transplantation. J Clin Endocrinol Metab 48: 101

    Article  PubMed  CAS  Google Scholar 

  5. Katz AI, Emmanuel DS (1978) Metabolism of polypeptide hormones by the normal kidney and in uremia. Nephron 22: 69

    Article  PubMed  CAS  Google Scholar 

  6. Lucci MS, Bengele HH, Solomon S (1975) Suppressive action of prolactin on renal response of volume expansion. Am J Physiol 229: 81

    PubMed  CAS  Google Scholar 

  7. Ijaiya K (1979) TSH and PRL response to thyrotrophin-releasing hormone in children with chronic renal failure undergoing hemodialysis. Arch Dis Child 54: 937

    Article  PubMed  CAS  Google Scholar 

  8. Spanos E, Colston KW, Evans IMS, Galante LS, Macauley SJ, Mclntyre I (1976) Effect of prolactin on vitamin D metabolism. Mol Cell Endocrinol 5: 163

    Article  PubMed  CAS  Google Scholar 

  9. Samaan NA, Freeman RM (1970) Growth hormone levels in severe renal failure. Metabolism 10: 102

    Article  Google Scholar 

  10. Hasegawa K, Matsushita Y, Otomo S, Hamada N, Nishizawa Y, Okamoto T, Morii Bi, Wada M (1975) Abnormal response of thyrotropin and growth hormone to thyrotropin releasing hormone in chronic renal failure. Acta Endocrinol 79: 635

    PubMed  CAS  Google Scholar 

  11. Gulyassy PF, Peters JH, Liu SC, Ryan PM (1968) Hemodialysis and plasma amino acid composition in chronic renal failure. Am J Clin Nutr 21: 565

    PubMed  CAS  Google Scholar 

  12. DeFronzo RA, Andres R, Edgar P, Gordon-Walker W (1972) Carbohydrate in uremia: a review. Medicine 52: 469

    Article  Google Scholar 

  13. Saenger P, Widemann E, Schwartz E, Korthschmitz S, Lewy E, Riggio RR, Rubin AL, Stenzel KH, New MI (1974) Somatomedin and growth after renal transplantation. Pediatr Res 8: 163

    PubMed  CAS  Google Scholar 

  14. Scanion MF, Smith BR, Hall R (1978) Thyroid-stimulating hormone: neuro-regulation and clinical application (part I). Clin Sei 55: 1

    Google Scholar 

  15. Franchimont P (1972) In: Hall R, Werner I, Holgate H (eds) Thyrotropin releasing hormone, vol I, Karger, Basel, p 139

    Google Scholar 

  16. Collu R, Clermont RJ, Ducharme JR (1976) Effects of thyrotropin releasing hormone on prolactin, growth hormone and corticosteron secretions in adult male rats treated with phenobarbital or morphine. Eur J Pharmacol 37: 133

    Article  PubMed  CAS  Google Scholar 

  17. Siassi F (1975) Thesis PHD, University of California, Los Angeles

    Google Scholar 

  18. Chen JC, Vidt DG, Zorn EM, Halberg MC, Wieland RG (1970) Pituitary-Leyding cell function in uremic males. J Clin Endocrinol 31: 14

    Article  CAS  Google Scholar 

  19. Guevara A, Vidt DG, Halberg MC, Zorn EM, Pohlman C, Wieland RG (1969) Serum gonadotropin and testosterone levels in uremic males undergoing intermittent dialysis. Metabolism 18: 1062

    Article  PubMed  CAS  Google Scholar 

  20. Faiman H, Winter JSD (1974) In: Grumbach MM, Grave CD, Mayer FE (eds) The control of the onset of the puberty. Wiley & Sons, New York, p 32

    Google Scholar 

  21. Mortimer CH, Besser GM, Goldie DJ, Hook J, McNeilly AS (1974) The TSH, FSH and prolactin response to continuous infusion of TRH and the effects of oestrogen administration in normal males. Clin Endocrinol (Oxf) 3: 97

    Article  CAS  Google Scholar 

  22. Lim VS, Fang VS, Katz AJ, Refetoff S (1977) Thyroid dysfunction in chronic renal failure. A study of the pituitary-thyroid axis and peripheral turnover kinetics of thyroxine and triiodothyronine. J Clin Invest 60: 522

    Article  PubMed  CAS  Google Scholar 

  23. Weissei, M, Stummvoll HK, Kglbe P, Höf er R (1979) Baßal and TRH-stimulated thyroid and pituitaxy hormones in various d,egress of renal insufficiency. Acta. Endocrinol (Copenh) 90: 23

    Google Scholar 

Download references

Authors
  1. F. Perfumo
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. M. Giusti
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. R. Gusmano
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. G. Giordano
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Kinderdialyse, Universitäts-Kinderklinik Köln, Joseph-Stelzmann-Str. 9, Köln 41, 5000, Germany

    Monika Bulla Frau Priv.-Doz. (Scientific Chairman and Editor) (Scientific Chairman and Editor)

Rights and permissions

Reprints and permissions

Copyright information

© 1982 Springer-Verlag Berlin Heidelberg

About this paper

Cite this paper

Perfumo, F., Giusti, M., Gusmano, R., Giordano, G. (1982). Study of Pituitary Secretion Using the Thyrotrophin-Releasing Hormone Test in Uremic Prepubertal Children. In: Bulla, M. (eds) Renal Insufficiency in Children. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-68144-8_17

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-68144-8_17

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-68146-2

  • Online ISBN: 978-3-642-68144-8

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation