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Arthritis pp 137-143 | Cite as

Enzyme Histochemical Demonstration of Certain Cell Populations in Synovium Using Plastic-Embedded Whole Rat Joints

  • W. Hermanns
  • L. C. Schulz

Abstract

Recent results in experimental arthritis research point to the possible importance of blood-born cells in the pathogenesis of chronic polyarthritis. Westerhellweg and Mohr [27], in adjuvant arthritis of rats, and Mohr and Wessinghage [14], in cases of human chronic polyarthritis, observed neutrophil granulocytes in the immediate vicinity of pannus-mediated destruction of articular cartilage. Autoradiographic studies in experimental allergic arthritis of guinea pigs led Ricken et al. [20] to assume that part of the hyperplastic synovial lining cells are progeny of myelogenic monocytes. Both these cell types possess fairly characteristic enzyme markers. Neutrophils show a comparatively high activity of naphthol-AS-D-chloroacetate-esterase [23], while monocytes/macrophages, on the other hand, are characterized by a diffuse reaction product of α-naphthyl-butyrateesterase [1].

Keywords

Enzyme Histochemistry Glycol Monomethyl Ether Ethylene Glycol Monomethyl Ether Monobutyl Ether Glycol Monobutyl Ether 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1981

Authors and Affiliations

  • W. Hermanns
  • L. C. Schulz

There are no affiliations available

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