Nitrates III pp 396-400 | Cite as

Influence of Isosorbide Dinitrate and Mononitrate on the Ejection Fraction and Wall Motion Parameters at Rest and Under Exercise in Patients with Coronary Heart Disease

  • M. Stauch
  • P. Kress
  • H. Geffers
  • W. Nechwatal
  • F. Bitter
  • H. Sigel
  • W. E. Adam

Abstract

blood pool scintigraphy is a convenient method for the evaluation of cardiac function as expressed by the ejection fraction (EF) of the left ventricle (LV). Other parameters, such as peak ejection rate, peak filling rate, regional motility, and distribution of phases of the time activity curves subjected to a Fourier analysis are also used for the analysis of the functional state [1, 2, 4, 5]. blood pool scintigraphy is also suitable for the study of LV function after various drugs, since in contrast to the first pass technique and perfusion scintigraphy it may easily be repeated several times with one load of isotope-labeled erythrocytes.

Keywords

Depression Ischemia Radionuclide Cardiol Isosorbide 

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References

  1. 1.
    Adam WE, Meyer G, Bitter F, Kampmann H, Stauch M, Paiva M (1974) Camera-cinematography: A nuclear medicine procedure for imaging heart kinetics. J Nucl Biol Med 18: 53Google Scholar
  2. 2.
    Adam WE, Sigel H, Geffers H, Kampmann H, Bitter F, Stauch M (1977) Analyse der regionalen Wandbewegung des linken Ventrikels bei koronarer Herzkrankheit durch ein nichtinvasives Verfahren ( Radionuklid-Kinematographie ). Z Kardiol 66: 545Google Scholar
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    Borer JS, Bacherach SL, Green MV, Kent KM, Epstein SE, Johnston GS (1977) Real-time radionuclide cineangiography in the noninvasive evaluation of global and regional left ventricular function at rest and during exercise in patients with coronary artery disease. N Engl J Med 296: 839PubMedCrossRefGoogle Scholar
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    Geffers H, Adam WE, Bitter F, Sigel H, Kampmann H (1977) Data processing and functional imaging in radionuclide ventriculography. Int. Conference on Data Processing and Medical Imaging. Nashville 1977Google Scholar
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    Sigel H, Geffers H, Kress P, Bitter F, Adam WE, Stauch M (1979) Über die Erfassung regionaler Funktionsstörungen des linken Ventrikels durch nuklearmedizinische Methoden. Herz Kreislauf 11: 102Google Scholar
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    Stauch M, Grewe N (1979) Die Wirkung von Isosorbiddinitrat, Isosorbid-2- and 5-Mononitrat auf das Belastungs-EKG und auf die Hämodynamik während Vorhofstimulation bei Patienten mit Angina pectoris. Z Kardiol 68: 687 - 693PubMedGoogle Scholar
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    Stauch M, Sigel H, Geffers H, Bitter F, Adam WE (1978) Radionuklid-Ventrikulographie. II. Klinische Ergebnisse, Parameter der globalen Ventrikelfunktion. Nuklearmedizin 17: 211Google Scholar
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    Stauch M, Adam WE, Geffers H, Sigel H, Bitter F, Kress P (1979) Austreibungsfraktion und Motilität des linken Ventrikels in Ruhe und unter Belastung vor und nach Molsidomin. In: Lochner W, Bender F (eds) Molsidomin. Urban and Schwarzenberg, Munich Vienna Baltimore, pp 111–118Google Scholar
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    Stauch M, Kress P, Geffers H, Nechwatal W, Bitter F, Adam WE (to be published) Evaluation of regional and global left ventricular function with gated blood pool scintigraphy under exercise; comparison with other methods. Adv CardiolGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1981

Authors and Affiliations

  • M. Stauch
  • P. Kress
  • H. Geffers
  • W. Nechwatal
  • F. Bitter
  • H. Sigel
  • W. E. Adam

There are no affiliations available

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