Changes in Neurotransmitter Synthesizing Enzymes During Regenerative, Compensatory, and Collateral Sprouting of Central Catecholamine Neurons in Adult and Developing Rats

  • D. J. Reis
  • R. A. Ross
  • L. Iacovitti
  • G. Gilad
  • T. H. Joh
Part of the Proceedings in Life Sciences book series (LIFE SCIENCES)


It is evident that the recovery of function following injury of the central nervous system (CNS) must relate to cellular processes by which synaptic transmission is modified morphologically and also by mechanisms facilitating chemical neurotransmission. While there has been a resurgence of interest in morphological concomitants of recovery of function, less is known about the changes in neurotransmitter biosynthetic enzymes following injury and their possible role in functional recovery.


Tyrosine Hydroxylase Olfactory Bulb Axonal Injury Locus Ceruleus Olfactory Tubercle 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1981

Authors and Affiliations

  • D. J. Reis
    • 1
  • R. A. Ross
    • 2
  • L. Iacovitti
    • 3
  • G. Gilad
    • 4
  • T. H. Joh
    • 1
  1. 1.Laboratory of Neurobiology, Department of NeurologyCornell University Medical CollegeNew YorkUSA
  2. 2.Department of BiologyFordham UniversityNew YorkUSA
  3. 3.Department of Anatomy and NeurobiologyWashington UniversitySt. LouisUSA
  4. 4.Department of Isotope ResearchWeizmann Institute of ScienceRehovetIsrael

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