Retinoids pp 385-388 | Cite as

Retinoid and Skin Cancer Prevention

  • L. Schnitzler
  • J. L. Verret


Relation between vitamin A and cancer is formerly known; the development of synthetic derivatives of vitamin A (synthetic retinoids) as an approach to prophylaxis of neoplasias has been continuing for over ten years (2, 9,10); the aromatic retinoid has in vitro or in animals an inhibiting action against cutaneous neoplasias (1). It appears therefore very interesting to test this drug in the prevention of cutaneous epitheliomas in human dermatoses with a high risk of cancer.


Basal Cell Carcinoma Actinic Keratosis Xeroderma Pigmentosum Skin Cancer Prevention Synthetic Retinoid 
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  1. 1.
    Bollag W (1974) Therapeutic effects of an aromatic retinoid acid analog on chemically induced skin papillomas and carcinomas of mice. Eur J Cancer 10: 731–737PubMedGoogle Scholar
  2. 2.
    Peck LP (1980) Retinoids in dermatology. Arch Dermatol 116: 283–284PubMedCrossRefGoogle Scholar
  3. 3.
    Schnitzler L, Hy R, Schubert B, Eon F, Baudoux C (1976) Xeroderma pigmentosum–présentation clinique de trois familles angevines. Bull Soc Fr Dermatol 4: 306–308Google Scholar
  4. 4.
    Schnitzler L, Schubert B, Verret JL, Belperron P, Bernat M (1977) Naevomatose basocellulaire chez deux jumelles. Pédiatrie 1: 29–44Google Scholar
  5. 5.
    Schnitzler L, Schubert B, Verret JL, Emeriau M, Brunet A (1977) Epitheliomatose familiale de Ferguson Smith. Ann Dermatol Vénéréol 104: 206–216PubMedGoogle Scholar
  6. 6.
    Schubert B, Verret JL, Morer Th, Schnitzler L (1977) Troubles pigmentaires dans un cas de porokératose de Mibelli disséminée. Ann Dermatol Vénéréol. 104: 887–892PubMedGoogle Scholar
  7. 7.
    Schnitzler L, Baudoux C, Eon F, Verret JL (1980) Essai de prévention de la dégénérescence épithéliomateuse dans les xeroderma pigmentosum (retinoide aromatique). Résultats dans 5 cas angevins. Congrès des dermatologistes de langue française, Tunis (June 1979 ). Ed. SAGEP, TunisGoogle Scholar
  8. 8.
    Schnitzler L, Schubert B, Verret JL (1980) Essai de prévention des épithéliomas cutanés par le rétinoide aromatique. Ann Dermatol Vénéréol 107: 657–663PubMedGoogle Scholar
  9. 9.
    Sporn MB, Newton DL (1979) Chemoprevention of cancer with retinoids. Fed Proc 38: 2528–2534PubMedGoogle Scholar
  10. 10.
    Sporn MB (1980) Retinoids and cancer prevention. In: Carcinogenesis, Vol. 5, Slaga TJ (ed), 99–109Google Scholar

Copyright information

© Springer-Verlag 1981

Authors and Affiliations

  • L. Schnitzler
  • J. L. Verret

There are no affiliations available

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