Immunological Features of Psoriasis: Effects of Ro 10-9359, Concanavalin A (ConA), Pokeweed Mitogen (PWM) and Methotrexate (MTX) on Cultivated Lymphocytes
The heterogeneous complex of chronic inflammatory diseases with different underlying causes for the initiation of specific lesions seems to be accompanied and perpetuated by antigen-driven production of nonspecific polyclonal antibody formation (3, 6). Hypotheses have been set up involving an impairment of suppressor cells, increase of specific helper cells or an increase in lymphokine secretion. Some of these suggestions have been made for psoriasis as well (4, 5, 9).
KeywordsMethotrexate Psoriasis Retinoid Dermatol Concanavalin
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