Surface Antigens of Pluripotent and Committed Haemopoietic Stem Cells
Blood cells are formed from stem cells which occur in low numbers in the bone marrow and spleen. A certain fraction of the stem cells is capable of giving rise to all types of blood cells. These are defined as the “pluripotent stem cells”. A more mature cell type which is still capable of extensive proliferation but which is restricted in its maturation to a single blood cell line is defined as the “committed stem cell”.
KeywordsBone Marrow Cell Congenic Mouse Mouse Bone Marrow Cell Region Antigen Colony Assay
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