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Performance, Wall Dynamics and Coronary Function of the Left Ventricle in Hypertensive Heart Disease

  • Conference paper
The Heart in Hypertension

Part of the book series: International Boehringer Mannheim Symposia ((BOEHRINGER))

Abstract

Arterial hypertension is the most frequent of left ventricular pressure load in man [1–4]. Its cardiac consequences closely depend on the degree of myocardial hypertrophy and on the progression of coronary artery disease [3, 4]. There have been relatively few reports [5, 6] on cardiac performance in human hypertension, in part because the disease in often asymptomatic and not thought to justify left ventricular catheterization. This study was, therefore, undertaken to investigate the cardiac manifestations of essential hypertension with special reference to left ventricular (LV) function, wall geometry, coronary hemodynamics, and myocardial energy demand. Moreover, the role of ventricular mass, volume, mass-to-volume ratio, and wall stress on the oxygen demand of the human LV myocardium has been studied in various clinical conditions of the chronic hypertrophic heart. The results indicate that systolic wall stress, as a consequence of the degree of ventricular hypertrophy, plays the predominant role in ventricular function and overall myocardial energy demand in chronic hypertrophic heart disease.

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Authors
  1. B. E. Strauer
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Editors and Affiliations

  1. Medizinische Klinik I, Universität München Klinikum Großhadern, Marchioninistraße 15, D-8000, München 70, Germany

    Bodo Eckehard Strauer

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© 1981 Springer-Verlag Berlin Heidelberg

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Strauer, B.E. (1981). Performance, Wall Dynamics and Coronary Function of the Left Ventricle in Hypertensive Heart Disease. In: Strauer, B.E. (eds) The Heart in Hypertension. International Boehringer Mannheim Symposia. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-67922-3_18

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  • DOI: https://doi.org/10.1007/978-3-642-67922-3_18

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-10496-4

  • Online ISBN: 978-3-642-67922-3

  • eBook Packages: Springer Book Archive

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