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Releasability — a New Dimension in Basophil and Mast Cell Reactivity

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New Trends in Allergy

Abstract

The factors which influence the allergic response are complex and only partially understood. At the level of the mast cell and basophil, the amount of cell-bound IgE and the concentration of antigen are important. These two measurable parameters are not sufficient however to determine the response of a basophil to an antigenic stimulus. The purpose of this presentation is to discuss the concept of “releasability”: first, to review its application to the human basophil system; second, to present data in which we try to assess “releasability” in human skin; and third, to note some of the literature which is related to this concept.

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Authors and Affiliations

  1. Institut für klinische Immunologie, Inselspital, Bern, Switzerland

    M. C. Conroy

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  1. M. C. Conroy
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Editors and Affiliations

  1. Dermatologische Klinik und Poliklinik, Ludwig-Maximilians-Universität, Frauenlobstr. 9, D-8000, München 2, Germany

    Johannes Ring  & Günter Burg  & 

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© 1981 Springer-Verlag Berlin Heidelberg

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Conroy, M.C. (1981). Releasability — a New Dimension in Basophil and Mast Cell Reactivity. In: Ring, J., Burg, G. (eds) New Trends in Allergy. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-67807-3_5

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  • DOI: https://doi.org/10.1007/978-3-642-67807-3_5

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-10346-2

  • Online ISBN: 978-3-642-67807-3

  • eBook Packages: Springer Book Archive

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