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Vasoactive Mediators in Contact Sensitivity

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New Trends in Allergy

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Abstract

The function of vasoactive substances, especially of histamine, in the development of allergic reactions has been extensively studied and their role in anaphylactic reactions convincingly established [1]. Initially, their role in delayed hypersensitivity was also presumed and investigated [23]. However, the failure of antihistaminic drugs to influence the manifestation of cell-mediated immune reactions [10] and the discovery of lymphokines as putative mediators of this type of hypersensitivity [6] diverted the attention of scientists to the latter substances.

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Author information

Authors and Affiliations

  1. Pharma Research Dept., F. Hoffmann-La Roche & Co. Ltd., Switzerland

    L. Polak

  2. Dermatological Clinic, University of Basle, Switzerland

    T. Rufli

Authors
  1. L. Polak
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  2. T. Rufli
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Editors and Affiliations

  1. Dermatologische Klinik und Poliklinik, Ludwig-Maximilians-Universität, Frauenlobstr. 9, D-8000, München 2, Germany

    Johannes Ring  & Günter Burg  & 

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© 1981 Springer-Verlag Berlin Heidelberg

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Polak, L., Rufli, T. (1981). Vasoactive Mediators in Contact Sensitivity. In: Ring, J., Burg, G. (eds) New Trends in Allergy. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-67807-3_31

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  • DOI: https://doi.org/10.1007/978-3-642-67807-3_31

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-10346-2

  • Online ISBN: 978-3-642-67807-3

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