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Disturbed Regulation of Aldosterone and Sodium Excretion in a Subgroup of Essential Hypertensives

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Hypertension: Mechanisms and Management

Part of the book series: International Boehringer Mannheim Symposia ((BOEHRINGER))

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Abstract

The phenomenon of low plasma renin activity in approximately 25% of essential hypertensives has initiated a great deal of interest into investigating signs of mineralocorticoid excesss in these patients. The results obtained were highly controversial. However, several abnormalities in mineralocorticoid production in patients with essential hypertension have been reported by the groups of Melby [12] and Genest [5, 6] and Luetscher [2, 4] demonstrating an inappropriate suppression of aldosterone secretion in essential hypertensives by sodium loading.

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References

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Authors
  1. A. Helber
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  2. G. Wambach
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  3. W. Hummerich
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  4. G. Bönner
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  5. K. A. Meurer
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  6. W. Kaufmann
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Editor information

Editors and Affiliations

  1. I. Medizinische Klinik und Poliklinik, Johannes-Gutenberg-Universität Mainz, Langenbeckstraße 1, D-6500, Mainz, Germany

    Thomas Philipp  & Armin Distler  & 

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© 1980 Springer-Verlag Berlin Heidelberg

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Helber, A., Wambach, G., Hummerich, W., Bönner, G., Meurer, K.A., Kaufmann, W. (1980). Disturbed Regulation of Aldosterone and Sodium Excretion in a Subgroup of Essential Hypertensives. In: Philipp, T., Distler, A. (eds) Hypertension: Mechanisms and Management. International Boehringer Mannheim Symposia. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-67712-0_20

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  • DOI: https://doi.org/10.1007/978-3-642-67712-0_20

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-10171-0

  • Online ISBN: 978-3-642-67712-0

  • eBook Packages: Springer Book Archive

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