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Beeinflussung des venösen Systems des großen Kreislaufs durch Stimulation und Blockade von Alpha- und Beta-Rezeptoren

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25 Jahre DGAI

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Zusammenfassung

Seit mehreren Jahrzehnten ist bekannt, daß adrenerge Pharmaka eine Venokonstriktion bewirken. Dieser Befund wurde erstmals im Jahre 1913 von Gunn und Chavasse [18] erhoben und ist seitdem in einer nicht mehr übersehbaren Zahl von Untersuchungen bestätigt worden [z.B. 3, 14, 32, 33, 38, 46, 49]. Allerdings gibt es einige wichtige Aspekte, die umstritten sind, so z.B. die Differenzierung von alpha-und beta-adrenergen Wirkungen auf das kapazitiv-venöse System. Nach dem Konzept von Ahlquist [1] führt eine Stimulation von Alpha-Rezeptoren zur Vasokonstriktion und eine Stimulation von Beta-Rezeptoren zur Vasodilatation. Dieses Konzept hat zwar das Verständnis der Reaktion des arteriellen Systems auf Katecholamine sehr erleichtert, aber es ist keineswegs klar, inwieweit sich dieses Konzept auch auf das kapazitiv-venöse System übertragen läßt.

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Authors
  1. E. R. Müller-Ruchholtz
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Editors and Affiliations

  1. Universität Würzburg, Josef-Schneider-Str. 2, 8700, Würzburg, Germany

    Karl-Heinz Weis (Vorstand des Instituts für Anästhesiologie) (Vorstand des Instituts für Anästhesiologie)

  2. Knappschafts-Krankenhaus, In der Scharnau 23/25, 4630, Bochum-Langendreer, Germany

    Günther Cunitz

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© 1980 Springer-Verlag Berlin Heidelberg

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Müller-Ruchholtz, E.R. (1980). Beeinflussung des venösen Systems des großen Kreislaufs durch Stimulation und Blockade von Alpha- und Beta-Rezeptoren. In: Weis, KH., Cunitz, G. (eds) 25 Jahre DGAI. Anaesthesiologie und Intensivmedizin / Anaesthesiology and Intensive Care Medicine, vol 130. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-67698-7_3

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  • DOI: https://doi.org/10.1007/978-3-642-67698-7_3

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-10140-6

  • Online ISBN: 978-3-642-67698-7

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