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Chirurgisches Forum’80 pp 209–212Cite as

Hemmung der Magensekretion durch intervenöses Gastric Inhibitory Polypeptid (GIP) beim Menschen

Inhibition of Gastric Secretion by i.v. Gastric Inhibitory Polypeptide (GIP) in Man

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Part of the book series: Langenbecks Archiv für Chirurgie ((FORUMBAND,volume 80))

Zusammenfassung

Intraduodenal verabreichte Säure stimuliert die Serum-GIP-Konzentration beim Hund und Menschen dosisabhängig (1). Da GIP die pen- tagastrinstimulierte Säuresekretion in denervierten Funduspouches signifikant hemmt (2), wurde vermutet, daß GIP ein physiologischer Regulator der Säuresekretion ist. In der vorliegenden Studie untersuchten wir daher den Effekt von intravenösem Gastric Inhibitory Polypeptid (GIP) sowohl auf die pentagastrin- als auch auf die nahrungsstimulierte Magensekretion beim Menschen.

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Literatur

  1. Ebert, M.D., Illmer, K., Creutzfeldt, W.: Release of Gastric inhibitory Polypeptide (GIP) by Intraduodenal Acidification in Rats and Humans and Abolishment of the Incretin Effect of Acid by GIP-Antiserum in Rats. Gastroenterology 76, 515–52 3 (1979)

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  2. Soon-Shion, P., Debas, H.T., Brown, J.C.: Cholinergic inhibition of Gastric Inhibitory Polypeptide (GIP) Action. Gastro¬enterol. 76, No. 5. Part. 2, 1052

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  3. Creutzfeldt, W., Ebert, R., Willms, B., Frerichs, H., Brown, J.C.: Gastric inhibitory polypeptide (GIP) and insulin in obesity: increased response to stimulation and defective feedback control of serum levels. Diabetologia 14, 1 5–24 (19 78)

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Author information

Authors and Affiliations

  1. Aus der Klinik für Allgemeinchirurgie, Universität Göttingen (Direktor: Prof. Dr. H.-J. Peiper), Germany

    Dr. med. A. Schafmayer, H. D. Becker, H. W. Börger, E. F. Coelle & R. Arnold

  2. Abteilung für Gastroenterologie, Klinik für Innere Medizin, Germany

    W. Creutzfeldt

  3. Klinik für Allgemeinchirurgie, Universität Göttingen, Goßlerstraße 10, D-3400, Göttingen, Germany

    Dr. med. A. Schafmayer

Authors
  1. Dr. med. A. Schafmayer
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  2. H. D. Becker
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  3. H. W. Börger
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  4. E. F. Coelle
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  5. R. Arnold
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  6. W. Creutzfeldt
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Editor information

Editors and Affiliations

  1. Chirurgische Universitätsklinik, Im Neuenheimer Feld 110, D-6900, Heidelberg, Germany

    Fritz Linder

  2. Chirurgische Universitätsklinik, 3550, Marburg/Lahn, Germany

    Hans-Dietrich Röher

  3. Abt. Experimentelle Chirurgie, Chirurgische Universitätsklinik, Im Neuenheimer Feld 347, D-6900, Heidelberg, Germany

    Ulrich Mittmann

  4. Auerfeldstraße 29, D-6900, Frankfurt/Main, Germany

    Herbert Junghanns

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© 1980 Springer-Verlag Berlin · Heidelberg

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Schafmayer, A., Becker, H.D., Börger, H.W., Coelle, E.F., Arnold, R., Creutzfeldt, W. (1980). Hemmung der Magensekretion durch intervenöses Gastric Inhibitory Polypeptid (GIP) beim Menschen. In: Linder, F., Röher, HD., Mittmann, U., Junghanns, H. (eds) Chirurgisches Forum’80. Langenbecks Archiv für Chirurgie, vol 80. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-67617-8_42

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  • DOI: https://doi.org/10.1007/978-3-642-67617-8_42

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-10035-5

  • Online ISBN: 978-3-642-67617-8

  • eBook Packages: Springer Book Archive

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