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13N-L-Amino Acids Synthesized Enzymatically for in vivo Metabolic Studies

  • A. S. Gelbard
Conference paper

Abstract

Short-lived, positron-emitting radionuclides of nitrogen and carbon may be generated with a cyclotron and used to label biologically active compounds such as amino acids for in vivo metabolic studies. The 10-min half-life of nitrogen-13 results in relatively small radiation exposures to the patient; but it requires that the chemist develop new and rapid procedures to synthesize adequate amounts of radiolabeled compounds.

Keywords

Enzymatic Synthesis Glutamate Dehydrogenase Cyanogen Bromide Label Amino Acid Amic Acid 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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Copyright information

© Springer-Verlag Berlin Heidelberg 1980

Authors and Affiliations

  • A. S. Gelbard
    • 1
  1. 1.Biophysics LaboratoryMemorial Sloan-Kettering Cancer CenterNew YorkUSA

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