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Can CO2 Be Actively Eliminated by the Lungs?

  • G. H. Gurtner
  • R. J. Traystman
Conference paper
Part of the Proceedings in Life Sciences book series (LIFE SCIENCES)

Abstract

A few years ago we presented our observation that in dogs, during rebreathing under conditions of no gas exchange, the alveolar \({{\text{P}}_{C{O_2}}}\) was higher than the \({{\text{P}}_{C{O_2}}}\) in the mixed venous blood (Gurtner et al., 1969). The phenomenon had been originally described by Bohr in 1891 who found that alveolar \({{\text{P}}_{C{O_2}}}\) was higher than arterial \({{\text{P}}_{C{O_2}}}\) when 5% to 10% CO2 was present in the inspired air. A similar observation had also teen made by Jones et al. (1967) during rebreathing experiments in exercising man a few years prior to our observations. Subsequently the pehnomenon has been reported by several groups of investigators including Guyatt et al. (1973) who did experiments similar to our own, and by Jennings and Chen (1975) who found results similar to those of Bohr. Recently, the phenomenon has been demonstrated to exist during normal gas exchange by Robertson and Hlastala (1977).

Keywords

Base Excess Mixed Venous Blood Severe Hypercapnia Alveolar Capillary Membrane Wien Effect 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1980

Authors and Affiliations

  • G. H. Gurtner
  • R. J. Traystman
    • 1
  1. 1.Depts. of Medicine and Environmental Health SciencesThe Johns Hopkins Medical InstitutionsBaltimoreUSA

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