Epidemiological and Immunogenetic Studies of Multiple Sclerosis in Japan
Multiple sclerosis (MS) is distributed over the world in a unique geographical pattern, with Japan and other Asian countries belonging to the low risk areas. Systematic prevalence studies, besides those of Japan , are lacking. Some reports of the clinical manifestations suggest a modification in Asian MS [2, 3, 16]. Since the environmental factors differ immensely between Asia (Japan) and the West, it is essential to cover these areas in obtaining various epidemiological parameters.
KeywordsNeurol Nigeria Measle Blindness Myelitis
Unable to display preview. Download preview PDF.
- 3.Kuroiwa Y, Shibasaki H (1973) Clinical studies of multiple sclerosis in Japan. Neurology (Minneap) 23:609–617Google Scholar
- 4.Kuroiwa Y, Shibasaki H (1976) Epidemiologic and clinical studies of multiple sclerosis in Japan. Neurology (Minneap) 26(6–2): 8–10Google Scholar
- 5.Kuroiwa Y, Igata A, Itahara K, Koshijima S, Tsubaki T, Toyokura Y, Shibasaki H (1975) Nationwide survey of multiple sclerosis in Japan. Clinical analysis of 1084 cases. Neurology (Minneap) 25:845–851Google Scholar
- 6.Kuroiwa Y, Hung TP, Landsborough D, Park CS, Singhal S, Soemargo S, Vejjajiva A, Shibasaki H (1977) Multiple sclerosis in Asia. Neurology (Minneap) 27:188–192Google Scholar
- 10.Okinaka S, Tsubaki T, Kuroiwa Y, Toyokura Y, Imamura Y, Yoshikawa M (1958) Multiple sclerosis and allied diseases in Japan. Neurology (Minneap) 8:756–763Google Scholar
- 12.Saito S, Naito S, Kawanami S, Kuroiwa Y (1976) HLA studies on multiple sclerosis in Japan. Neurology (Minneap) 26(6–2): 49Google Scholar
- 13.Sasazuki T, Ohono Y, Iwamoto I (1976) Association of HLA-D antigens with multiple sclerosis. In: Kuroiwa Y (ed) Annual report of MS research committee, Japan, Min Health Welfare Japan, pp 153–156Google Scholar
- 15.Shibasaki H, Okihiro M, Kuroiwa Y (1978) Multiple sclerosis among Orientals and Caucasians in Hawaii: A reappraisal. Neurology (Minneap) 28:113–118Google Scholar