Experimental Brain Injury in the Dog: Pathophysiological Correlation

  • R. J. Clubb
  • R. Maxwell
  • S. Chou

Abstract

Despite the utilization of standardized brain injury created by the inflation and subsequent deflation of an epidural balloon, two general response patterns were observed: 1. Absence of significant postdeflation intracranial hypertension and prolonged survival. 2. Postdeflation intracranial pressure (ICP) rise exceeding 40 torr, plateau waves, and brain death within several hours of deflation. This paper aims to provide insight into the causes of the variability in response sto a standardized injury by correlating physiological behavior with autopsy findings.

Keywords

Ischemia Urea Neurol Mannitol Pentobarbital 

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References

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Copyright information

© Springer-Verlag Berlin Heidelberg 1980

Authors and Affiliations

  • R. J. Clubb
  • R. Maxwell
  • S. Chou

There are no affiliations available

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