Abstract
The use of isotopic tracers has been recommended by several authors in the past 10 years for the study of lactate metabolism in mammalian species (1). It is relevant to this Symposium devoted to anaerobic metabolism and lactic acid (1) to specify the significance of some parameters used in these studies, (2) to summarise the results obtained with these techniques, and (3) to comment on some practical or theoretical problems arising from this methodology.
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References
MINAIRE, Y.: Origine et destinee du lactate plasmatique. J. Physiol. (Paris) 66, 229–257 (1973)
KREISBERG, R.: Glucose-lactate inter-relations in man. N. Engl. J. Med. 287, 132–137 (1976)
FREMINET, A., POYART, C.: Lactate-glucose interrelations, glucose recycling and the Cori-cycle in normal fed rats. Pfluegers Arch. 316, 25–31 (1975)
FREMINET, A., BURSAUX, E., POYART, C.: Effect of elevated lactataemia on the rates of lactate turnover and oxidation in rats. Pfluegers Arch. 346, 75–86 (1974)
WIENER, R., SPITZER, J.J.: Lactate metabolism following severe hemorrhage in the conscious dog. Am. J. Physiol. 227, 58–62 (1974)
WOLFE, R.R., MILLER, H.I., SPITZER, J.J.: Glucose and lactate kinetics in burn shock. Am. J. Physiol. 232, E415-E418 (1977)
ISSEKUTZ, B., SHAW, W.S., ISSEKUTZ, A.C.: Lactate metabolism in resting and exercising dogs. J. Appl. Physiol. 40, 312–319 (1976)
ELDRIDGE, F.L., T’SO, L., CHANG, H.: Relationships between turnover rate and blood concentration of lactate in normal dogs. J. Appl. Physiol. 316–320 (1974)
KREBS, H.A., HEMS, R., WEIDEMANN, M.J., SPEAKE, R.N.: The fate of isotopic cerbon in kidney cortex synthesizing glucose from lactate. Biochem. J. 101, 242–249 (1966)
HANSON, P.W.: The choice of animal species for studies of metabolic regulation. Nutr. Rev. 32, 1–8 (1974)
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Freminet, A., Poyart, C., Leclerc, L. (1980). Is the Use of Isotopic Tracers Valid for the Study of Lactate Metabolism in vivo. In: Moret, P.R., Weber, J., Haissly, JC., Denolin, H. (eds) Lactate. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-67525-6_9
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DOI: https://doi.org/10.1007/978-3-642-67525-6_9
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