A nationwide screening program for hypothyroidism is run in Denmark by measuring TSH from PKU cards of all newborns (N.J. Brandt 1978, personal communication). Until autumn 1978 among 55 000 newborns screened 12 cases of congenital hypothyroidism were detected. This frequency agrees well with data of other groups in Europe. The design of the study is almost identical to the scheme of Illig (see p. 179 ff).


Europe Hypothyroidism Sonal Hyperthyroidism Thyroxine 


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  1. Barke JL, Laurence NL, Bennett J, Robinson S (1975) Endocrine syndromes produced by neonatal hyperthyroidism, hypothyroidism or altered nutrition and effects seen in untreated progeny. In: Fisher DA, Burrow GN (eds) Perinatal thyroid physiology and disease. Raven Press, New York pp 79–116Google Scholar
  2. Sato T, Suzuki Y, Taketani T, Kazumasa I, Nakajima H (1977) Age-related change in pituitary threshold for TSH release during thyroxine replacement therapy for cretinism. J Clin Endocrinol Metab 44:553–559PubMedCrossRefGoogle Scholar

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© Springer-Verlag Berlin Heidelberg 1980

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  • D. Schönberg

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