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Surgical Treatment of Amenorrhea-Galactorrhea

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Neurovascular Surgery

Part of the book series: Advances in Neurosurgery ((NEURO,volume 7))

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Abstract

The association of amenorrhea and galactorrhea with pituitary tumors has been known for many years (1), but only occasionally did such patients come to the attention of the neurosurgeon. The recent development of the sensitive radioimmunoassay for prolactin (3) marked a major advancement, and it was soon shown that the most common hormone secreted in excess by pituitary tumors was prolactin. Furthermore, it rapidly became apparent that small pituitary tumors called microadenomas, which hypersecreted prolactin and produced amenorrhea and galactorrhea in the young woman, were often the cause of infertility (4, 6).

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References

  1. FORBES, A.P., HENNEMAN, P.H., GRISWOLD, G.C., et al.: Syndrome characterized by galactorrhea, amenorrhea and low urinary FSH: Comparison with acromegaly and normal lactation. J. Clin. Endocrinol. Metab. 14, 265–271 (1954)

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  3. HWANG, P., GUYDA, H., FRIESEN, H.A.: A radioimmunoassay for human prolactin. Proc. Natl. Acad. Sci. U.S.A. 68, 1902–1906 (1971)

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© 1979 Springer-Verlag Berlin Heidelberg

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Brodkey, J.S., Pearson, O.H., Manni, A. (1979). Surgical Treatment of Amenorrhea-Galactorrhea. In: Marguth, F., Brock, M., Kazner, E., Klinger, M., Schmiedek, P. (eds) Neurovascular Surgery. Advances in Neurosurgery, vol 7. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-67455-6_18

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  • DOI: https://doi.org/10.1007/978-3-642-67455-6_18

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-67457-0

  • Online ISBN: 978-3-642-67455-6

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