Abstract
The presence of a vasodilator in human urine was first described by Abelous and Bardier in 1909. Subsequently, the presence of kallikrein was described by Frey and Kraut (1928) in human urine and it was assumed to be the vasodilator of Abelous and Bardier.
Keywords
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsPreview
Unable to display preview. Download preview PDF.
References
Abelous, J.E., Bardier, E.: Les substances hypotensives de l’urine humaine normale. Comptl. Rend. Soc. Biol. 66,511 (1909)
Adetuyibi, A.: Some studies on kallikrein in urine. Ph.D. Thesis. University of Cambridge 1972
Adetuyibi, A, Mills, I.H.: Relation between urinary kallikrein and renal function, hypertension, and excretion of sodium and water in man. Lancet 1972/II, 203–207
August, J.T, Nelson, D.H, Thorn, G.W.: Response of normal subjects to large amounts of aldosterone. J. Clin. Invest. 38,1549–1555 (1958)
Barraclough, M.A, Mills, I. H.: Effect of bradykinin on renal function. Clin. Sci. 28, 69–14 (1965)
Bartter, F.C., Pronove, P, Gill, J.R, MacCardle, J.C.: Hyperplasia of the juxtaglomerular complex with hyperaldosteronism and hypokalaemic alkalosis. Am. J. Med. 33, 811–828 (1962)
Beaven, V.H, Pierce, J.V, Pisano, J.J.: A sensitive isotopic procedure for the assay of esterase activity: measurement of human urinary kallikrein. Clin. Chim. Acta 32,67–73 (1971)
Bevan, D.R, MacFarlane, N.A.A, Mills, I.H.: The dependence of urinary kallikrein excretion on renal artery pressure. J. Physiol. 241, 34–35P (1974)
Bono, E. de, Mills, I. H.: Simultaneous increases in kallikrein in renal lymph and urine during saline infusion. J. Physiol. 241,127–128P (1974)
Croxatto, H.R, Roblero, J, Albertini, R, Corthorn, J, San Martin, M, Porcelli, G.: The kallikrein-kinin system in renal hypertension. In: Chemistry and biology of the kallikrein-kinin system in health and disease. Pisano, J.J., Austen, K.F. (eds.), pp. 389–397. Fogarty Internat. Center Proc. No. 27. Washington: U.S. Gov. Printing Office 1977
Croxatto, H.R, Albertini, R, Arriagada, R, Roblero, J, Rojas, M, Rosas, R.: Renal urinary kallikrein in normotensive and hypertensive rats during enhanced excretion of water and electrolytes. Clin. Sci. Mol. Med. 51,259s–261s (1976)
Data, J.L., Chang, L.C.T, Nies, A.S.: Alteration of canine renal vascular response to hemorrhage by inhibitors of prostaglandin synthesis. Am. J. Physiol. 230,940–945 (1976)
Donker, A.J.M., Arisz, L, Brentjens, J.R.H., Van der Hem, G.K, Hollemans, H.J.G.: The effect of indomethacin in kidney function and plasma renin activity in man. Nephron 17, 288–296 (1976)
Edwards, O.M, Adetuyibi, A, Mills, I.H.: Kallikrein excretion during the ‘escape’ from the sodium retaining effect of fludrocortisone. J. Endocrinol. 59, xxxiv (1973)
Elebute, O.A, Mills, I.H.: Urinary kallikrein in normal and hypertensive pregnancies. In: Hypertension in pregnancy. Lindheimer, M.D, Katz, A.I, Zuspan, F.P. (eds.), pp. 329–338. New York: Wiley and Sons 1976
Elliot, R, Nuzum, F.R.: Urinary excretion of a depressor substance (kallikrein of Frey and Kraut) in arterial hypertension. Endocrinology 18,462–474 (1934)
Frey, E. K, Kraut, H.: Ein neues Kreislaufhormon und seine Wirkung. Naunyn Schmiedebergs Arch. Exp. Pathol. Pharmacol. 133,1 (1928)
Frey, E.K, Kraut, H, Werle, E.: Kallikrein (Padutin). Stuttgart: Enke 1950
Gill, J.R, Jr., Flolich, J.C., Bowden, R.E, Taylor, A.A, Keiser, H.R, Seyberth, H.W, Oates, J.A, Bartter, F.C.: Bartter’s syndrome: A disorder characterized by high urinary prostaglandins and a dependence of hyperreninemia on prostaglandin synthesis. Am. J. Med. 61, 43–51 (1976)
Gordon, R.D, Symonds, E.M, Wilmshurst, E.G., Pawsey, C.G.K.: Plasma renin activity, plasma angiotensin, and plasma and urinary electrolytes in normal and toxaemic pregnancy, including a prospective study. Clin. Sci. Mol. Med. 45,115–127 (1975)
Greco, A.V, Porcelli, G, Croxatto, H.R.: Kallikrein excretion in diverse types of hypertension. In: Chemistry and biology of the kallikrein-kinin system in health and disease. Pisano, J.J, Austen, K.F. (eds.), pp. 439–440. Fogarty Internat. Center Proc. No. 27. Washington: U.S. Gov. Printing Office 1977
Keiser, H.R, Margolius, H.S, Brown, R, Rhamey, R, Foster, J.: Urinary kallikrein in patients with renovascular hypertension. In: Chemistry and biology of the kallikrein-kinin system in health and disease. Pisano, J.J, Austen, K.F. (eds.), pp. 423–426. Fogarty Internat. Center Proc. No. 27. Washington: U.S. Gov. Printing Office 1977
Keiser, H.R, Andrews, M.J, Jr., Guyton, R.A, Margolius, H.S., Pisano, J.J.: Urinary kallikrein in dogs with constriction of one renal artery. Proc. Soc. Exp. Biol. Med. 151, 53–56 (1976)
Lechi, A, Covi, G, Lechi, C, Mantero, F, Scuro, L.A.: Urinary kallikrein excretion in Bartter’s syndrome. J. Clin. Endocrinol. Metab. 43,1175–1178 (1976)
Lennane, R.J, Carey, R.M., Goodwin, T.J., Peart, W.S.: A comparison of natriuresis after oral and intravenous sodium loading in sodium-depleted man: evidence for a gastrointestinal or portal monitor of sodium intake. Clin. Sci. Mol. Med. 49,437–440 (1975)
Levy, S.B, Lilley, J.J, Frigon, R.P, Stone, R.A.: Urinary kallikrein and plasma renin activity as determinants of renal blood flow. The influence of race and dietary sodium intake. J. Clin. Invest. 60,129–138 (1977)
MacFarlane, N.A.A, Adetuyibi, A, Mills, I.H.: The radioimmunoassay of bradykinin in the measurement of kallikrein in urine. J. Endocrinol. 58, xxv (1973)
MacFarlane, N.A.A, Adetuyibi, A, Mills, I.H.: Changes in kallikrein excretion during arterial infusion of angiotensin. J. Endocrinol. 61, lxxii (1974)
Margolius, H.S., Pisano, J.J., Geller, R, Sjoerdsma, A.: Altered urinary kallikrein excretion in human hypertension. Lancet 1971II, 1063–1065
Margolius, H.S., Horwitz, D, Geller, R.G, Alexander, R.W, Gill, J.R, Pisano, J.J, Keiser, H.R.: Urinary kallikrein excretion in normal man. Relationships to sodium intake and sodium-retaining steroids. Circ. Res. 35, 812–819 (1974a)
Margolius, H.S., Horwitz, D, Pisano, J.J, Keiser, H.R.: Sodium, water, and kallikrein excretion in man. Acta Physiol. Lat. Am. 24,464–468 (1974b)
Margolius, H.S., Horwitz, D, Pisano, J.J., Keiser, H.R.: Urinary kallikrein excretion in hypertensive man. Relationships to sodium intake and sodium-retaining steroids. Circ. Res. 35, 820–825 (1974c)
Margolius, H.S, Chao, J, Kaizu, T.: The effects of aldosterone and spironolactone on renal kallikrein in the rat. Clin. Sci. Mol. Med. 51,279s–282s (1976)
Marin-Grez, M, Carretero, O.A.: A method for measurement of urinary kallikrein. J. Appl. Physiol. 32,428–431(1972)
Marin-Grez, M, Cottone, P, Carretero, O.A.: Evidence for an involvement of kinins in regulation of sodium excretion. Am. J. Physiol. 223,794–796 (1972)
Matsuda, Y, Moriya, H, Moriwaki, C, Fujimoto, Y, Matsuda, M.: Fluorometric method for assay of kallikrein-like arginine esterases. J. Biochem. 79,1197–1200 (1976)
Mills, I.H.: Sodium-retaining steroids in non-oedematous patients. Production of odemea and heart-failure. Lancet 19621,1264–1267
Mills, I.H.: The non-aldosterone hormonal control of sodium. In: Hormones and the kidney. Williams, P.C. (ed.), pp. 17–24. Memoirs of the Society for Endocrinology No. 13. London, New York: Academic Press 1963
Mills, I.H., Barkham, D.W.: The effect of 9a-fluorohydrocortisone on the response to angiotensin infusions in man. International Congress Series No. 51, Abstract No. 310. Amsterdam: Excerpta Medica 1962
Mills, I.H, Wilson, R.J.: Antagonism by noradrenaline of the changes in renal function associated with development of resistance of the renal vasculature to the arterial infusion of angiotensin. Proc. Int. Union Physiol. Sci. Vol. IX, Abstract No. 1167. Munich: German Physiological Society 1971
Mills, I.H, Ward, P. E.: The relationship between kallikrein and water excretion and the conditional relationship between kallikrein and sodium excretion. J. Physiol. 246, 695–707 (1975)
Mills, I.H, MacFarlane, N.A.A, Ward, P.E, Obika, L.F.O.: The renal kallikrein-kinin system and the regulation of salt and water excretion. Fed. Proc. 35,181–188 (1976)
Mills, I.H, Obika, L.F.O.: A novel effect of intrarenal infusion of a non-vasoconstrictor dose of noradrenaline on renal function: relationship to renal kallikrein and prostaglandin. J. Physiol. 267,21–22P (1977)
Mills, I.H, Obika, L.F.O., Newport, P.: Stimulation of the renal kallikrein-kinin system by vasoactive substances and its relationship to the excretion of salt and water. Contributions to Nephrology 12,132–144 (1978)
McGiff, J.C., Terragno, N.A, Malik, K.U, Lonigro, A.J.: Release of a prostaglandin E-like substance from canine kidney by bradykinin. Circ. Res. 31,36–43 (1972)
McGiff, J.C, Itskovitz, H. D, Terragno, A, Wong, P.Y.-K.: Modulation and mediation of the action of the renal kallikrein-kinin system by prostaglandins. Fed. Proc. 35, 175–180 (1976)
Moriya, H.: A colorimetric method for the estimation of urinary kallikrein. Jpn. J. Clin. Med. 22, 2659–2664 (1964)
Nekrasova, A.A, Lantsberg, L.A, Chernova, N.A, Khukharev, V.V.: The kinin system of the kidneys in various physiological states in healthy persons and in patients with essential hypertension. Kardiologiya 10,9–15 (1970a)
Nekrasova, A.A, Chernova, N.A, Sharapov, U.B, Kovaleva, N.T.: Kallikrein level in the urine and some indices of kidney function. Urol. Nefrol. (Mosk.) 3,12–16 (1970b)
Olsen, U.B, Ahnfelt-Ronne, I.: Bumetanide induced increase of renal blood flow in conscious dogs and its relation to local renal hormones (PGE, kallikrein, and renin). Acta Pharmacol. Toxicol. 38,219–228(1976)
Orloff, J, Handler, J, Bergstrom, S.: The effect of prostaglandin (PGE1) on the permeability response of toad bladder to vasopressin, theophylline, and adenosine 3′, 5′-monophosphate. Nature (London) 205, 397 (1965)
Padfield, P.L, Allison, M.E.M, Brown, J.J, Lever, A.F, Luke, R.G, Robertson, C.C, Robertson, J.I.S., Tree, M.: Effect of intravenous frusemide on plasma renin concentration: suppression of response in hypertension. Clin. Sci. Mol. Med. 49,353–358 (1975)
Patak, R. V, Mookerjee, B. K, Bentzel, C. J, Hysert, P. E, Babej, M, Lee, J. B.: Antagonism of the effects of furosemide by indomethacin in normal and hypertensive man. Prostaglandins 10(4), 649–659(1975)
Peart, W.S.: Possible relationship between salt metabolism and the angiotensin system. In: Essential hypertension. Bock, K.D, Cottier, P.T. (eds.), pp. 112–120. Berlin, Heidelberg, New York: Springer 1960
Roberts, P. S.: Measurement of the rate of plasmin action on synthetic substrates. J. Biol. Chem. 232,285 (1958)
Roblero, J, Croxatto, H.R, Garcia, R, Corthorn, J, de Vitro, R.: Kallikrein-like activity in perfusates and urine of isolated rat kidneys. Am. J. Physiol. 231,1383–1389 (1976a)
Roblero, J, Croxatto, H.R, Albertini, R.B.: Release of renal kallikrein to the perfusate by isolated rat kidney. Experientia 32,1440–1441 (1976b)
Rumpf, K.W, Frenzel, S, Lowitz, H.D, Scheler, F.: The effect of indomethacin on plasma renin activity in man under normal conditions and after stimulation of the renin angiotensin system. Prostaglandins 10(4), 641–648 (1975)
Scicli, A.G, Carretero, O.A, Hampton, A, Cortes, P, Oza, N.B.: Site of kininogenase secretion in the dog nephron. Am. J. Physiol. 230, 533–536 (1976)
Seino, M, Abe, K, Otsuka, Y, Saito, T, Irokawa, N, Yasujima, M, Chiba, S, Yoshinaga, K.: Urinary kallikrein excretion and sodium metabolism in hypertensive patients. Tohoku J. Exp. Med. 116,359–367 (1975)
Seino, M, Abe, K, Sakurai, Y, Irokawa, N, Yasujima, M, Chiba, S, Otsuka, Y, Yoshinaga, K.: Effect of spironolactone on urinary kallikrein excretion in patients with essential hypertension and in primary aldosteronism. Tohoku J. Exp. Med. 121,111–119 (1977)
Sever, P.S, Birch, M, Osikowska, B, Tunbridge, R.D.G.: Plasma-noradrenaline in essential hypertension. Lancet 19771,1078–1081
Talamo, R.C, Haber, E, Austen, K.F.: A radio-immunoassay for bradykinin in plasma and synovial fluid. J. Lab. Clin. Med. 74,816–827 (1969)
Ward, P.E.: Studies of the renal kinin systems. Ph.D. Thesis. University of Cambridge 1974
Ward, P.E, Mills, I.H.: Distribution of renal kininases in relation to the kallikrein-bradykinin system and water excretion. J. Endocrinol. 67,60P (1975)
Ward, P.E, Schultz, W, Reynolds, R. C, Erdös, E. G.: Metabolism of kinins and angiotensins in the isolated glomerulus and brush border of rat kidney. Lab. Invest. 36, 599–606 (1977)
Wong, P.Y, Talamo, R.C, Williams, G.H, Colman, R. W.: Response of the kallikrein-kinin and renin-angiotensin systems to saline infusion and upright posture. J. Clin. Invest. 55, 691–698 (1975)
Zinner, S.H, Margolius, H.S, Rosner, B, Keiser, H.R, Kass, E.H.: Familial aggregation of urinary kallikrein concentration in childhood: relation to blood pressure, race, and urinary electrolytes. Am. J. Epidemiol. 104,124–132 (1976)
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1979 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Mills, I.H. (1979). Renal Kallikrein and Regulation of Blood Pressure in Man. In: Erdös, E.G. (eds) Bradykinin, Kallidin and Kallikrein. Handbook of Experimental Pharmacology, vol 25 / 1. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-67301-6_15
Download citation
DOI: https://doi.org/10.1007/978-3-642-67301-6_15
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-67303-0
Online ISBN: 978-3-642-67301-6
eBook Packages: Springer Book Archive