Advertisement

Assets and Limitations of Animal Models

Conference paper
Part of the Human Genetics, Supplement book series (HUMAN GENETICS, volume 1)

Abstract

Animals, as models to be studied instead of man, have been used for a long time and have been essential for research in many areas. For instance, the success of genetics would not have been possible without Drosophila, and pharmacology not without cats and dogs. Most current pharmacologic research is done by using laboratory mice or rats, i. e., animals that are genetically not well defined. However, there are various kinds of defined laboratory strains.

Keywords

Inbred Strain Recombinant Inbred Recombinant Inbred Strain High Alcohol Consumption Congenic Line 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. Eleftheriou, B. E.: Psychopharmacogenetics. New York, London: Plenum 1975Google Scholar
  2. Eriksson, K.: Behavioral and physiological differences among rat strains specially selected for their alcohol consumption. Ann. N.Y. Acad. Sci. 197, 32–41 (1972)PubMedCrossRefGoogle Scholar
  3. Green, E. L.: Handbook on genetically standardized mice, 2nd ed. Bar Harbor: Jackson Laboratory 1968Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1978

Authors and Affiliations

  1. 1.Department of PharmacologyUniversity of TorontoTorontoCanada

Personalised recommendations