Tumor Cell Mediated Degradation In Vitro of Antitumor Antibodies

  • Y. Keisari
  • I. P. Witz
Conference paper
Part of the Haematology and Blood Transfusion / Hämatologie und Bluttransfusion book series (HAEMATOLOGY, volume 23)


An in vivo interaction between tumor cells and humoral immune components was strongly supported by the findings that malignant tumor cells of human and animal origin are coated in vivo with Ig molecules. In some tumor host systems it was possible to show that at least some of the tumor bound Ig molecules expressed antibody activity against the tumor cells [13].


Ammonium Sulfate Lysosomal Enzyme Rabbit Antiserum Lower Molecular Weight Range Antitumor Antibody 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1979

Authors and Affiliations

  • Y. Keisari
    • 1
  • I. P. Witz
    • 2
  1. 1.Laboratory of Immunobiology, National Cancer InstituteNational Institutes of HealthBethesdaUSA
  2. 2.Department of Microbiology, The George S. Wise Center for Life SciencesTel Aviv UniversityRamat Aviv, Tel AvivIsrael

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