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The Effect of Systolic Rise in Arterial Pressure on Stroke Volume and Aortic Flow

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The Arterial System

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Abstract

In many papers, the effect of arterial end diastolic pressure (afterload) on ventricular function has been studied [4, 5, 8,17, 28]. In all these experiments, afterload was varied before systole. Under conditions in situ, however, the heart encounters changes in pressure which occur during systole. Shortly after the onset of the primary pulse resulting from aortic flow [31], superimposed reflected pulse waves determine the further rise and time course of systolic aortic pressure. Such waves might depress flow and diminish stroke volume. The extent of this effect must depend on the properties of the heart, as far as its pumping function is concerned.

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References

  1. Bauer, R.D., Busse, R., Schabert, A., Summa, Y., Wetterer, E.: Methoden der Blutströmungsmessung in Physiologie und Klinik. Wiener Med. Wochenschr. 126, 225–260 (1976)

    Google Scholar 

  2. Baumann, KL, Reichel, H.: Time and rate dependence of the inotropic action of noradrenaline in the isolated guinea pig’s atrium. Pflügers Arch. 354, 339–348 (1975)

    Article  PubMed  CAS  Google Scholar 

  3. Broemser, Ph.: Über die optimalen Beziehungen zwischen Herztätigkeit und physikalischen Konstanten des Gefäßsystems. Z. Biol. 96, 1–10 (1935)

    Google Scholar 

  4. Bugge-Asperheim, B., Kill, F.: Cardiac response to increased aortic pressure. Scand. J. Clin. Lab. Invest. 24, 345–360 (1969)

    Article  PubMed  CAS  Google Scholar 

  5. Bugge-Asperheim, B., Kill, F.: Preloads contractility and afterload as determinants of stroke volume during elevation of aortic blood pressure in dogs. Cardiovasc. Res. 7, 528–541 (1973)

    Article  Google Scholar 

  6. Covell, J.W., Taylor, R.R., Sonnenblick, E.H., Ross, J. (Jr.): Series elasticity in the intact heart. Pflügers Arch. 357, 225–236 (1975)

    Article  PubMed  CAS  Google Scholar 

  7. Elzinga, G., Westerhof, N.: Pressure and flow generated by the left ventricle against different impedances. Circ. Res. 32, 178–186 (1973)

    PubMed  CAS  Google Scholar 

  8. Goodjer, A.V.N., Goodkind, M.J., Landry, A.B.: Ventricular response to a pressure load. Circ. Res. 10, 885–896 (1962)

    Google Scholar 

  9. Hill, A.V.: The heat of shortening and the dynamic constants of muscle. Proc. R. Soc. Lond. [Biol.] B 126, 136–169 (1938)

    Article  Google Scholar 

  10. Jacob, R., Kissling, G., Ohnhaus, E.E., Peiper, U., Segarra-Domenech, J.: Die „Kontraktilitä“des suffizienten Herzens unter rechtsventrikulärem Schrittmacherantrieb. Arch. Kreislaufforsch. 54, 192–215 (1967)

    Article  PubMed  CAS  Google Scholar 

  11. Kaufmann, R., Bayer, R., Fürniss, T., Krause, H., Tritthart, H.: Calcium-Movement Controlling cardiac contractility IL Analog computation of cardiac excitation-contraction coupling on the basis of calcium kinetics in a multicompartment model. J. Mol. Cell. Cardiol. 6, 543–559 (1974)

    Article  PubMed  CAS  Google Scholar 

  12. Kedem, J., Mahler, Y., Rogel, S.: The effect of heart rate on myocardial contractility during single and paired pulse stimulation in vivo. Arch. Int. Physiol. Biochim. 77, 880–892 (1969)

    Article  PubMed  CAS  Google Scholar 

  13. Kenner, Th.: Zur Frage der Optimierung in der Abstimmung zwischen Herztätigkeit und Kreislauf. Pacemaker Digest 13, 51–82 (1977)

    Google Scholar 

  14. Kenner, Th., Estelberger, W.: Zur Frage der optimalen Abstimmung der Herzkontraktion an die Eigenschaften des Arteriensystems. Verh. Dtsch. Ges. Kreislaufforsch. 42, 132–135 (1976)

    PubMed  CAS  Google Scholar 

  15. Kiwull, P., Rueadas, G., Reichel, H., Bleichert, A.: Der Einfluß definierter Druckstöße auf die Dynamik des Schildkrötenherzens. Pflügers Arch. 279, 228–238 (1964)

    Article  CAS  Google Scholar 

  16. Koch-Weser, J., Blinks, J.R.: The influence of interval between beats on myocardial contractility. Pharmacol. Rev. 15, 601–657 (1963)

    PubMed  CAS  Google Scholar 

  17. Levine, H.J., Forwand, St.A., Mclntyre, K.M., Schechter, E.: Effect of afterload on force velocity relations and contractile element work in the intact dog heart. Cir. Res. 18, 729–744 (1966)

    CAS  Google Scholar 

  18. Liedtke, A.J., Buoncristiani, J.F., Kirk, E.S., Sonnenblick, E.H., Urschel, Ch.W.: Regulation of cardiac output after administration of isoproterenol and ouabain: interactions of systolic impedance and contractility. Cardiovasc. Res. 6, 325–332 (1972)

    Article  PubMed  CAS  Google Scholar 

  19. Limbourg, P., Wende, W., Henrich, H., Peiper, U.: Frequenz-inotropie und Frank-Starling-Mechanismus am Hundeherzen in situ unter natürlichem und künstlichem Herzantrieb. Pflügers Arch. 322, 250–263 (1971)

    Article  PubMed  CAS  Google Scholar 

  20. Lundin, G.: Mechanical properties of cardiac muscle. Act. Physiol. Scand. 7 [Suppl. 20] 7–84 (1944)

    Google Scholar 

  21. Noble, M.I.N., Trenchard, D., Guz, A.: Effect of changing heart rate on cardiovascular function in the conscious dog. Circ. Res. 19, 206–213 (1966)

    Google Scholar 

  22. Reichel, H.: Kontraktilität und Elastizität des Herzmuskels als Modellvorstellung. Verh. Dtsch. Ges. Kreislaufforsch. 16, 13–15 (1950)

    Google Scholar 

  23. Reichel, H.: Muskelphysiologie. Berlin-Heidelberg-New York: Springer 1960

    Google Scholar 

  24. Reichel, H., Kapal, E.: Die Mechanik des Herzens bei Änderung des arteriellen Drucks. Z. Biol. 99, 581–589 (1939)

    Google Scholar 

  25. Reichel, H., Zimmer, F., Bleichert, A.: Die elastichen Eigenschaften des Skelett- und Herzmuskels in verschiedenen Phasen der Einzelzuckung. Z. Biol. 108, 188–195 (1956)

    PubMed  CAS  Google Scholar 

  26. Rumberger, E., Reichel, H.: The force-frequency relationship; a comparative study between warm- and cold blooded animals. Pflügers Arch. 332, 206–217 (1972)

    Article  PubMed  CAS  Google Scholar 

  27. Sonnenblick, E.H.: Force-velocity relation in mammalian heart muscle. Am. J. Physiol. 202, 931–939 (1962)

    PubMed  CAS  Google Scholar 

  28. Sonnenblick, E.H., Downing, S.V.: Afterload as a primary determinant of ventricular performance. Am. J. Physiol. 204, 604–610 (1963)

    PubMed  CAS  Google Scholar 

  29. Templeton, G.H., Nardizzi, L.R.: Elastic and viscous stiffness of the canine left ventricle. J. Appl. Physiol. 36, 123–127 (1974)

    PubMed  CAS  Google Scholar 

  30. Tritthart, H., Kaufmann, R., Volkmer, H.P., Bayer, R., Krause, H.: Camovement controlling myocardial contractility I. Voltage, current- and time- dependence of mechanical activity under voltage clamp conditions (cat papillary muscles and trabeculae). Pflügers Arch. 338, 207–231 (1973)

    Article  PubMed  CAS  Google Scholar 

  31. Wetterer, E., Kenner, Th.: Grundlagen der Dynamik des Arterienpulses. Berlin-Heidelberg-New York: Springer 1968

    Google Scholar 

  32. Wilcken, D.E.L., Charlier, A.A., Hoffman, J.I.E., Guz, A.: Effects of alteration in aortic impedance on the performance of the ventricles. Circ. Res. 14, 283–293 (1964)

    PubMed  CAS  Google Scholar 

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  1. Physiologisches Institut, Universität Hamburg, D-2000, Hamburg, Germany

    H. Reichel & K. Baumann

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  1. H. Reichel
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  2. K. Baumann
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  1. Institut für Physiologie und Kardiologie, Universität Erlangen-Nürnberg, D-8520, Erlangen, Waldstraße 6, Germany

    R. D. Bauer  & R. Busse  & 

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Reichel, H., Baumann, K. (1978). The Effect of Systolic Rise in Arterial Pressure on Stroke Volume and Aortic Flow. In: Bauer, R.D., Busse, R. (eds) The Arterial System. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-67020-6_21

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  • DOI: https://doi.org/10.1007/978-3-642-67020-6_21

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-08897-4

  • Online ISBN: 978-3-642-67020-6

  • eBook Packages: Springer Book Archive

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